This paper presents investigations on turning Ti–6Al–4V alloy withmulti-layer coated inserts. Turning of Ti–6Al–4V using uncoated, TiAlN coated, and TiAlN + cBN coated single and multi-layer coated tungsten carbide inserts is conducted, forces and tool wear aremeasured. 3D finite elementmodelling is utilized to predict chip formation, forces, temperatures and tool wear on these inserts. Modifie...

Abstract This work investigates heat transfer and entropy generation of a turbulent flow an Al 2 O 3 –Cu/water hybrid nanofluid in plain tube (PT) with classical (TPT) elliptical‑cut twisted tape (TECT) inserts. The pressure drop are investigated numerically at Re (7000–15,000), mass concentration (1–4%), the inlet temperature fluid (300 K). Further, total Bejan number examined = 7000 4%. obtai...

A circular tube fitted with novel corrugated spring tape inserts has been investigated. Air was used as the working fluid. thorough literature review done and this geometry not studied previously, neither experimentally nor theoretically. experimental investigation of enhanced can, therefore, be treated a new substantial contribution in open literature. Three different ratio depth study. Increa...

Numerical investigation has been carried out on heat transfer and friction factor characteristics of copper-water nanofluid flow in a constant heat-fluxed tube with the existence of new configuration of vortex generator using Computational Fluid Dynamics (CFD) simulation. Two types of swirl flow generator: Classical twisted tape (CTT) and Parabolic-cut twisted tape (PCT) with a different twist ...

Background: Tolmetin (Tol) is a pyrrole acetic acid derivative that acts as a highly effective topical anti-inflammatory agent. Topical administration of Tol is effective for the management of ocular inflammations.The aim of this study was to formulate and improve a topical ophthalmic delivery system of Tol. Materials and methods: In the present study, ocular inserts of Tol were prepared using ...

BACKGROUND Current methods of female surgical sterilisation require incisional surgery, general anaesthesia and a prolonged recovery time. We studied the safety and effectiveness of Essure pbc, a minimally invasive, transcervically placed micro-insert that occludes the Fallopian tubes, resulting in permanent female contraception. Device under study: The Essure pbc implant is a dynamically expan...

Microfluidic loops (i.e. closed fluid paths) pose specific practical challenges such as priming, introducing analytes or reagents in a controlled way and sampling products. In this technical note we address these three issues using a removable part of the microchannel that we call a 'capillary insert'.

Package insert of pharmaceutical drug is one of the most prioritized information for pharmacists to secure safety of patients. However, the color of character, size, font and so on are various company by company product to product from a viewpoint of visibility. It may be cause a serious accident in case visibility is unclear, although it is the most important information. Moreover, package ins...