BACKGROUND/AIMS The aim of this study was to evaluate the accuracy of 3-T magnetic resonance imaging (MRI) in locating rectal cancer, and to determine whether tumor location correlates with the incidence of pulmonary metastasis. MATERIALS AND METHODS A total of 146 patients with confirmed rectal adenocarcinoma underwent 3-T rectal MRI, and abdominal and chest computed tomography (CT) within 2...

Interleukin-2 (IL-2) has been shown to promote tumor-specific T-cell proliferation and differentiation but systemic administration of IL-2 results in significant toxicity. Therefore, a strategy that can specifically deliver IL-2 to the tumor location may alleviate concerns of toxicity. Because NKG2D ligands have been shown to be highly expressed in many cancer cells but not in healthy cells, we...

a malignant peripheral nerve sheath tumor (mpnst) is very rare, representing 3 - 10% of all soft tissue sarcomas. approximately half of all such tumors are diagnosed in patients with neurofibromatosis type 1 (nf1). the extremities are involved most commonly, and the patient’s age is usually 20 - 50 years. herein, we present a case of an mpnst that developed sporadically in an unusual location a...

background and objectives: involvement of lymph nodes is an important prognostic factor in the most cancers, including colorectal cancer. in the recent years, invasion to blood and lymphatic vessels has been shown to predict involvement of lymph nodes and the number of involved nodes has been less studied issue. the aim of this study was determination of the relationship between the size of col...

Among the rare bone tumors, the osteoblastoma is a fascinating tumor. The rarity, the predisposition to occur in any bone and the diagnostic dilemma makes this infrequent tumor interesting. It is sporadically reported in the literature and what is rarer is its occurrence in the pelvis. The unusual location and inconclusive radiographic findings with diffused diagnostic evidences delays the mana...

intra-operative management of thyroid gland in laryngeal cancer is controversial. to determine the rate of thyroid involvement in patients with laryngeal cancer treated by radical surgical excision, we reviewed the records during 1996-2000 in imam khomeini hospital, cancer institute, and amir alam hospital.we studied several factors such as age, gender, and tumor location, presence of thyroid i...