Awake surgery could be a useful modality for lesions locating in close proximity to the eloquent areas including primary motor cortex and pyramidal tract. In case with supplementary motor area (SMA) lesion, we often encounter with intraoperative motor symptoms during awake surgery even in area without positive mapping. Although the usual recovery of the SMA syndrome has been well documented, ra...

A major challenge in the diagnosis and treatment of brain tumors is tissue heterogeneity leading to mixed treatment response. Additionally, they are often difficult or at very high risk for biopsy, further hindering the clinical management process. To overcome this, novel advanced imaging methods are increasingly being adapted clinically to identify useful noninvasive biomarkers capable of dise...

Genomic analyses of late-stage human cancers have uncovered deletions encompassing 1p36, thereby providing an extensive body of literature supporting the idea that a potent tumor suppressor resides in this interval. Although several genes have been proposed as 1p36 candidate tumor suppressors, convincing evidence that their encoded products protect from cancer has been scanty. A recent function...

UNLABELLED Lymphoscintigraphy is performed before sentinel node (SN) biopsy for SN mapping. It is of clinical importance mainly if the tumor is located in body parts with ambiguous lymph node drainage. The purpose of this study was to assess the clinical benefit of fused SPECT/CT images to planar images for SN mapping. METHODS Thirty-four consecutive patients with cutaneous malignant melanoma...

g20 world brain mapping initiative (neuroscience/n-20) is putting brain mapping on the top of global economic issues the society for brain mapping, therapeutics, and brain mapping foundation are propelling therapeutic advances in nano-neurosurgery, nano-bio-electronics, artificial intelligence, neuro-supercomputing and ‘cross-pollination’ among the bio-medical sciences and engineering worldwide...

the focus of this study is to analyze the text world of omar khayyam's poetry by a novel approach called cognitive poetics. to examine the author’s/reader's text world, the study has employed freeman’s model (1998). she believes that conceptual mapping in literary texts can operate at three different levels including “attribute mapping,” “relational mapping,” and “system mapping.” through readi...

Cancers, especially of the neural tissue, are often deemed a death sentence. However, neither cellular and molecular mechanisms nor underlying causes fully defined. Despite what is currently known about various types brain tumors, it remains poorly understood how they spread cause collateral damage to other parts brain. This research focuses cerebrospinal fluid (CSF) leakage enzymes from cancer...