Curcumin, the active compound found in turmeric, is believed to delay development of diabetes through several mechanisms. This study aimed investigate if an aqueous extract turmeric can improve glucose uptake and uric acid mouse tissues vitro, after inclusion diet for four weeks. Fourteen adult male Swiss mice were divided into three groups. The first group was control (n=6) that given clean wa...

The aim of the present study was to develop a self-nanoemulsifying drug delivery system (SNEDDS) for the oral delivery of Zedoary turmeric oil (ZTO), an essential oil extracted from the dry rhizome of Curcuma zedoaria. Pseudo-ternary phase diagrams were constructed to identify the efficient self-emulsification regions. ZTO could serve as a partial oil phase with the aid of the second oil phase ...

Objective: Inflammation can be induced by microbiological, chemical, physical factors and plays roles in inflammatory diseases. Turmeric (Curcuma longa L.) has been widely used to provide a diverse array of biological activities, including anti-inflammatory, antimicrobial, also antioxidant. The extract (TE) anti-inflammatory potential was conducted using Lipopolysaccharide (LPS)-induced RAW264....

Turmeric has been studied and used as a plant derivate active ingredient for centuries. Several effects of turmeric have described, however the poor solubility its ingredients during formulation development may limit oral applicability. The aim research was to involve dietary supplement hard capsule containing (Curcuma longa) (ground powder from root standardized curcuminoid content) sodium ben...

Background Curcumin is the major active ingredient of Curcuma longa L., traditionally known as turmeric and has been shown to exhibit a wide range of pharmacological activities including anti-parasitic effect. However, it is found to be water-insoluble and has low bioavailability. The aim of this study was to explore the potential role of turmeric solved in olive oil either alone or in combinat...

The main components for tablet formulations are the fillers, binders, crushers, thinners and lubricants. Among these components, binders play a key role on powder cohesion properties during formation of granules. In this study, turmeric extract tablets were formulated using 15 g extract, 35 aerosil, 12.8 lactose, 1% magnesium stearate, 200 ml aquadest gelatin as binder. To evaluate effect formu...

The present study investigated the effect of curcumin, a phenolic compound with yellow color from Curcuma longa L., on the expression of the apoptosis-related genes [BAX (Bcl-2 associated protein X), PKB, p53, MDM2 (mouse double minute 2), caspase 9, c-Ski, smad1 and smad4] in hamster opisthorchiasis. On Opisthorchis viverrini infection treated with dietary curcumin apoptosis-related gene expre...

Snu-Yao Tsai et al., (2011) isolated the essential oils from the dried rhizomes of Curcuma aromatica salisb, Curcuma longa and Curcuma sichuanensis using simultaneous steam distillation and solvent extraction apparatus. Antioxidant studies were also carried out for these essential oils. Effectiveness for scavenging 1,1diphenyl-2-picrylhydrazyl radicals was found to be less in Curcuma aromatica ...

In the present work, essential oil has been obtained by Clevenger-type hydrodestillation from grounded curcuma rhizome (Rhizoma Curcumae) (Turkey) with hydromodulus 1:5 m/V during 180 minutes. The qualitative and quantitative composition of the oil was determined by GC-MS and GC-FID spectrometry. The antioxidant activity of the obtained oil was determined using DPPH assay just after adding DPPH...