amyloid-β (aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in alzheimer’s disease pathology.uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...

Condition monitoring and protection methods based on the analysis of the machine's current are widely used according to non-invasive characteristics of current transformers. It should be noted that, these sensors are installed by default in the machine control center. On the other hand, condition monitoring based on mathematical methods has been proposed in literature. However, they are model b...

This paper targets the content selection problem in generating appropriate information in the domain of in-car navigation. It describes an algorithm that models driver’s knowledge about roads and routes and uses this knowledge to tailor turn-by-turn instructions from a commercial routing service to those more suitable to the individual driver’s background. This content selection component is on...

My wife leased a 2002 Acura MDX with one of the first OEM in-dash nav systems. I have been a convert ever since – we’ve leased four Acuras now with in-dash nav, and I will not own a car without it. The software has improved with every vehicle. Even in my hometown, I use the “go home” feature constantly. GPS user testimonial circa 2005. (Cooley, 2005) Jeff Robbins Rutgers University, USA GPS: A ...

Pathogenic bacteria express distinct sets of genes at different stages in their life cycles; inappropriate expression of normally repressed genes during host colonization can interfere with bacterial survival.