The objective of this study was to explore the joint kinetics of upper extremities during wheelchair maneuvers. A high incidence of musculoskeletal injuries has been reported due to the overuse and high repetitive motion of wrist, elbow and shoulder during wheelchair propulsion. Studies have been conducted with the use of a dynamometer or treadmill to simulate propulsion on level or inclined su...

Serotonin (5-HT) is known to modulate motor outputs in a variety of animal behaviors. However, the downstream neural pathways of 5-HT remain poorly understood. We studied the role of 5-HT in directional change, or turning, behavior of fruit fly (Drosophila melanogaster) larvae. We analyzed light- and touch-induced turning and found that turning is a combination of three components: bending, ret...

T cells navigate complex microenvironments to initiate and modulate antigen-specific immune responses. While recent intravital microscopy study revealed that migration of T cells were guided by various tissue microstructures containing unique nanoscale topographical structures, the effects of complex nanotopographical structures on the migration of T cells have not been systematically studied. ...