BACKGROUND In twin-twin transfusion syndrome (TTTS), the donor and recipient fetus are exposed to differing volume loads and show discordant intertwin vascular compliance in childhood despite identical genotype. We hypothesized that discordance is prevented by intrauterine endoscopic laser ablation of placental anastomoses, which abolishes intertwin transfusion. We tested this by examining puls...

BACKGROUND Symptoms of congenital cytomegalovirus infection remains unclear. CASE CHARACTERISTICS Extremely low birth weight twins with twin-to-twin transfusion syndrome were infected with cytomegalovirus congenitally. OBSERVATION The donor showed neuronal impairment, whereas the recipient showed hepatic dysfunction. MESSAGE Intrauterine hemodynamics may be important in pathophysiology of...

Wijngaard, Jeroen P. H. M. van den, Asli Umur, Raymond T. Krediet, Michael G. Ross, and Martin J. C. van Gemert. Modeling a hydropic recipient twin in twin-twin transfusion syndrome. Am J Physiol Regul Integr Comp Physiol 288: R799–R814, 2005. First published November 11, 2004; doi:10.1152/ajpregu.00635.2004.— We developed a mathematical model of twin-twin transfusion syndrome (TTTS) that inclu...

Correct antepartum management of multifetal gestations is a critical skill for practitioners of obstetrics. This article reviews important issues surrounding these complicated pregnancies while discussing current management options and recommendations. Topics include antepartum surveillance, preterm labor prediction, diagnosis, and management, and special situations unique to multiple gestation...

There is a lack of research findings addressing the unique college admissions issues faced by twins and other multiples. The advantages and disadvantage twins face, as reported by college administrators, twins and families are reviewed. Next, recent research addressing twins' birth weight and neuromotor performance, transfusion syndrome markers, the vanishing twin syndrome and monozygotic (MZ) ...

Coronavirus infection (COVID-19) has quickly emerged as a global pandemic leading to critical health complications. The possibility and risk of vertical transmission this virus is still unclear, particularly it relates pregnant women their fetuses. Regarding scientific data, there insufficient research focused on COVID-19 complicated with hydrops fetalis intrauterine fetal demise. In study, we ...