نتایج جستجو برای: type 1b

تعداد نتایج: 1358922  

Journal: :The Journal of infectious diseases 1997
H E Vargas L F Wang T Laskus A Poutous R Lee A Demetris F Dodson A Casavilla J Fung T Gayowski N Singh I Marino J Rakela

The distribution of hepatitis C virus (HCV) genotypes was studied in 202 anti-HCV-positive liver transplant candidates with end-stage liver disease. HCV sequences were successfully amplified from 185 patients: In the first 100, the genotype was determined by direct sequencing in the NS5 region, and in the remaining 85, type-specific primers were used for genotyping. Eighty-five patients (46.0%)...

Journal: :Agronomy 2022

Soybean (Glycine max (L.) Merr.) oil is an important source of vegetable for supporting the human diet. However, high level polyunsaturated fatty acids in natural soybean renders unstable and thus susceptible to development unpalatable flavors trans acids. Therefore, reducing content increasing monounsaturated a longstanding target breeding. varieties with oleic acid are rare germplasm resource...

Journal: :The Journal of pharmacology and experimental therapeutics 2001
A J Mayorga A Dalvi M E Page S Zimov-Levinson R Hen I Lucki

The development of serotonin receptor knockout mice has provided an opportunity to study antidepressant drug effects in animals with targeted genetic deletion of receptors involved in antidepressant responses. In the current study, the effects of two types of antidepressant drugs, the selective serotonin reuptake inhibitors fluoxetine and paroxetine and the selective norepinephrine reuptake inh...

Journal: :The Biochemical journal 2006
Yuushi Okumura Masaki Hayama Etsuhisa Takahashi Mieko Fujiuchi Aki Shimabukuro Mihiro Yano Hiroshi Kido

Polyserase-1 (polyserine protease-1)/TMPRSS9 (transmembrane serine protease 9) is a type II transmembrane serine protease (TTSP) that possesses unique three tandem serine protease domains. However, the physiological function of each protease domain remains poorly understood. We discovered a new splice variant of polyserase-1, termed Serase-1B, which contains 34 extra amino acids consisting a SE...

Journal: :Molecular and cellular biology 1999
R Fenrick J M Amann B Lutterbach L Wang J J Westendorf J R Downing S W Hiebert

t(12;21) is the most frequent translocation found in pediatric B-cell acute lymphoblastic leukemias. This translocation fuses a putative repressor domain from the TEL DNA-binding protein to nearly all of the AML-1B transcription factor. Here, we demonstrate that fusion of the TEL pointed domain to the GAL4 DNA-binding domain resulted in sequence-specific transcriptional repression, indicating t...

Journal: :The Journal of Cell Biology 1977
M Kalina DC Pease

Normal rat kidney (NRK) cells infected with a temperature-sensitive (ts) mutant of mouse sarcoma virus (NRK [MSV-1b]) express the transformed phenotype when grown under permissive conditions, but acquire the normal phenotype when grown under restrictive conditions. Addition of 3', 5' cyclic adenosine monophosphate (cAMP) to NRK (MSV-1b) cells grown at the restrictive temperature results in morp...

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