there are much heterogeneity in the genetic variation of type 2 diabetes (t2d). the purpose of this study was to investigate the association of seven novel genetic loci identified in a recent genome-wide association studies (gwas) with t2d in chinese dong populations.a case-controlled study was performed in individuals of chinese dong nationality. the genotypes of pard3b (rs849230), loc729993 (...

background: transforming growth factor-beta 1(tgf-β1) t869c (rs1800470, the same below) gene polymorphism is notably relative with the development of diabetic nephropathy (dn)，and cc/ct genotype diabetic have higher frequency of than tt genotype diabetic. to find out individual risk factors in the two genotypes especially in susceptible genotype could provide more efficient and targeted prevent...

conclusions jytk combined with metformin improves some antioxidant indices (sod and mda), and decreases inflammation in patients with t2dm, suggesting that it can reduce the risk of diabetic complications. results all 112 patients, including 59 in the treatment group (jytk + metformin) and 52 controls (metformin only) completed the 26-week clinical trial. jykt plus metformin treatment increased...

conclusions mobile phone text messaging increased adherence to diabetes therapy and improved the clinical outcome in saudi patients with type 2 diabetes. results in addition to significant improvement in patients’ knowledge, mean fasting blood glucose level improved from 8.60 ± 3.16 to 7.77 ± 3.11 mmol/l and mean hba1c decreased from 9.9% ± 1.8% to 9.5% ± 1.7%. objectives we conducted a study t...

background: diabetic men have been claimed to have lower serum free testosterone (ft) concentrations than non-diabetic men. the aim of this study was to investigate if serum ft, luteinizing hormone (lh), and follicle stimulating hormone (fsh) concentrations are different in patients with type 2 diabetes mellitus compared with healthy men and to identify factors associated with low serum testost...

background: asymptomatic bacteriuria (asb) is common among women with diabetes. the aim of this study was determine the prevalence of and risk factors for asb in women with diabetes type 2 in shahre-kord city of iran. methods: in a six months period (april- september 2005), a total of 100 women with diabetes (type 2) and 100 healthy women without diabetes as control group were investigated for ...

background diabetic nephropathy is the most important cause of end stage renal disease (esrd). aldosterone is involved in renal damage through induction of fibrosis, inflammation and necrosis in the kidney tissue. previous studies have demonstrated that the combination of angiotensin receptor blocker (arb) and spironolactone (an anti-aldosterone drug) are efficient for albuminuria reduction. ob...

conclusions plasma se and gpx levels were lower in type two diabetic patients with macroalbuminuria and related to the stage of diabetic nephropathy. results plasma se and gpx concentrations were significantly lower in diabetic patients with macroalbuminuria than other study groups (p < 0.001). albuminuria (alb/cr in random urine sample) had a negative correlation with plasma se (r = -0.40, p =...

objective: to determine the level of lipoprotein (a) in diabetic patients comparing to control group. materials and methods: this cross-sectional study was conducted on the patients referred to endocrinology clinic of bu ali-sina hospital in 2009. 180 subjects including 90 diabetic and 90 healthy subjects as control group enrolled in this study. all diabetic patients had glycemic control. we me...