Introduction The increase in the use of breast feeding and the decrease in mothers' hospitalization in the past few years have caused  an increase in the infant bilirubin level, so it is necessary to introduce methods which can identify infants with higher risks of hyperbiliru binemia. The aim of this study is to determine the predictive value of measuring the umbilical cord bilirubin for patho...

background: in this study, we examined a new two step induction protocol for improving the differentiation of human umbilical cord blood-derived mesenchymal stem cells into neural progenitor cells. materials and methods: human umbilical cord blood-derived mesenchymal stem cells were first cultured in dulbecco’s modified eagle medium supplemented with 10% fetal bovine serum in a humidified incub...

The umbilical cord is a helical and tubular blood conduit connecting the foetus to the placenta. The umbilical cord achieves its final form by the 12th week of gestation and normally contains two arteries and a single vein, all embedded in Wharton's jelly. The structure of the umbilical cord receives only a cursory glance during many obstetric ultrasound examinations: with imaging limited to do...

BACKGROUND It has been established that presence of lean umbilical cord with reduced Wharton's jelly in sonographic scans is a fetal marker for risk of small for gestational age at birth. With improvement of ultrasound techniques, more studies have been investigating the alterations of the umbilical cord on pregnancy outcomes. OBJECTIVES To determine the reference ranges of the umbilical cord...

BACKGROUND Several agents have been used for neonatal umbilical cord care, but we did not find any study evaluating the effect of human milk on umbilical cord separation time. The purpose of this study was to compare the effect of topical application of human milk, ethyl alcohol 96%, and silver sulfadiazine on umbilical cord separation time in newborn infants. This study was undertaken place at...

introduction: it is well know that fetal distress is one of the important causes of fetus perinatal morbidity and mortality. in this study, we sought to evaluate the association between umbilical coiling index and fetal distress.material and method:this was a case- control study conducted on 90 term pregnant women. study group had fetal distress (abnormal fetal heart rate, meconium staining, ap...

background: human umbilical cord blood (hucb) is an acceptable and readily accessible source of stem cells. there is an ongoing interest in cord blood stem cell therapies; however, little is known about the possible unfavorable effects of laboratory modifications on the isolated hucb cells. the involvement of mirnas in several biological processes has been shown. the aim of this study was to ev...

introduction and objectives: annually one million newborns die due to the umbilical cord infection. thus, in this study, we aimed toevaluate the effect of topical aloe vera gel on umbilical cord complications. methods: this randomized clinical trial was performed in maternity ward of ghaem hospital, mashhad, iran the samples were selected through convenience sampling and were randomly divided i...

background: in recent years we have successfully adopted an in vitro hepatogenic differentiation of mesenchymal stem cells (mscs). in this protocol the biologically active hepatocyte-like cells were differentiated from the stem cells isolated from either bone marrow or umbilical cord blood (ucb) samples. the aim of the present study was to compare the efficiency of the hepatogenic differentiati...

I t is our anticipation and hope that stem cells will cure type 1 diabetes someday because of their limitless capacity to differentiate as needed into the vital tissue or organ. In theory, pluripotent cells have the capacity to reprogram a hostile immune response to tolerate pancreatic -cells and to regenerate pancreatic -cell mass. These two factors are the necessary ingredients for reversing ...