نتایج جستجو برای: undesirable indices

تعداد نتایج: 98129  

Journal: :JCI insight 2018
Jie An Liping Wang Michael L Patnode Vanessa K Ridaura Jonathan M Haldeman Robert D Stevens Olga Ilkayeva James R Bain Michael J Muehlbauer Erin L Glynn Steven Thomas Deborah Muoio Scott A Summers James E Vath Thomas E Hughes Jeffrey I Gordon Christopher B Newgard

Current obesity interventions suffer from lack of durable effects and undesirable complications. Fumagillin, an inhibitor of methionine aminopeptidase-2, causes weight loss by reducing food intake, but with effects on weight that are superior to pair-feeding. Here, we show that feeding of rats on a high-fat diet supplemented with fumagillin (HF/FG) suppresses the aggressive feeding observed in ...

2015
Kang Soo Lee Kyung Heon Lee Sang Bok Kim Byung Hang Ha Jin Ho Jung Hyung Jin Sung Sang Soo Kim

Optofluidics is one of the most remarkable areas in the field of microfluidic research. Particle manipulation with optofluidic platforms has become central to optical chromatography, biotechnology, and μ-total analysis systems. Optical manipulation of particles depends on their sizes and refractive indices (n), which occasionally leads to undesirable separation consequences when their optical m...

1992
Eleni Stroulia Murali Shankar Ashok K. Goel Louise Penberthy

We analyze the blame-assignment task in the context of experience-based design and redesign of physical devices. We identify three types of blame-assignment tasks that differ in the types of information they take as input: the design does not achieve a desired behavior of the device, the design results in an undesirable behavior, a specific structural element in the design misbehaves. We then d...

2017
M. R. Shahriari

Today, banks, as intermediaries, seek to attract and allocate resources to obtain greater benefit. Therefore, the bank assessment is considered as an important subject in the banking industry. Data envelopment analysis is an effective technique in evaluating the efficiency of decision-making units. There are factors among banking indices (such as receivables from resource allocation) that are i...

2016
Bertrand Iooss

A functional risk curve gives the probability of an undesirable event in function of the value of a critical parameter of a considered physical system. In several applicative situations, this curve is built using phenomenological numerical models which simulate complex physical phenomena. Facing to cpu-time expensive numerical models, we propose to use the Gaussian process model to build functi...

2015
K. Edwin Sheppard Susan D. Boon

This study examined whether personality factors are associated with people’s appraisals of the costs and benefits of romantic revenge. Our goal was to extend our understanding of variables that influence individuals’ decisions to get even with romantic partners. Undergraduates (N = 130) completed the HEXACO personality inventory, the Vengeance Scale, and questionnaires examining people’s belief...

Journal: :Channels 2015
Sharan K Bagal Brian E Marron Robert M Owen R Ian Storer Nigel A Swain

Voltage-gated sodium (NaV) channels are a family of transmembrane ion channel proteins. They function by forming a gated, water-filled pore to help establish and control cell membrane potential via control of the flow of ions between the intracellular and the extracellular environments. Blockade of NaVs has been successfully accomplished in the clinic to enable control of pathological firing pa...

Journal: :Blood 1983
H Chang S M Ewert R M Bookchin R L Nagel

Fifteen compounds reported to be inhibitors of gelation or sickling were studied by standard methods. These tests included (1) the determination of the solubility of deoxyhemoglobin S or Csat, (2) evaluation of sickling in whole SS blood at various pO2s, (3) measurement of the oxygen affinity of hemoglobin and blood, and (4) examination of red cell indices and morphology. Among the 4 noncovalen...

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