Goltz syndrome or focal dermal hypoplasia is a rare syndrome with mesoectodermal hypoplasia. This syndrome is an X-linked dominant disorder with involvement of the cutaneous, ocular, dental and skeletal systems. The most significant feature of this disease is connective tissue dysplasia. Here, we report a 30-year old woman who presented with congenital unilateral linear atrophic areas on her tr...

Institute for Hematopathology, 22547 Hamburg, Germany, Referenceand Consultation Center for Gynecoand Breast Pathology, 22547 Hamburg, Germany, Institute for Dermatopathology, 22547 Hamburg, Germany, Institute of Pathology, 33098 Paderborn, Germany, Institute of Bioinformatics, University of Muenster, 48149 Muenster, Germany, Klinik for Dermatology, University of Muenster, 48149 Muenster, Germa...

BACKGROUND First described in 1872, syringomas are common intraepidermal sweat gland tumors most often found in women during adolescence. Frequent involvement areas are the lower eyelids and malar areas; vulvar involvement is relatively rare. These lesions often appear as small, separate, yellowish papules of about 1-3 mm in size and are generally associated with increased vulvar discomfort and...

Chondroid syringoma is a rare benign adnexal tumor of skin accounting for only about 1% commonly encountered tumors. It contains both epithelial and mesenchymal stromal component, hence refered as mixed skin.Its cytological features have rarely been published in the literature. A mucoid aspirate, abundant chondromyxoid matrix material, components were suggested diagnostic criteria. We report he...

Inflammatory linear verrucous epidermal nevus (ILVEN) is a unilateral skin disorder which usually manifests in infancy or childhood. Female predominance, frequent leg involvement, pruritus, resistance to treatment, and a psoriasiform histologic pattern are other common characteristics of this disease. Atypical presentations of ILVEN have been described and include late onset in life, wide...

Chondroid syringoma (CS) is a rare, benign, appendageal tumor with diagnostic feature of myxochondroid stroma supporting eccrine and apocrine epithelial structures. The usual presentation is a painless, slowly growing mass, typically located in the head and neck region. It usually affects middle-aged and older male patients. Because of its unremarkable clinical presentation it is often overlook...

primary or secondary hyperparathyroidism can present with a brown tumor of the mandible. involvement of other skull and facial bones is extremely rare. only a few cases with brown tumor of the orbital bones have been reported. an is year old girl with primary hyperparathyroidism presented with unilateral exophthalmos caused by brown tumor of the orbital roof, lite patient had a 1.5 cm palpable ...