background stress urinary incontinence (sui), the most common type of urinary incontinence (ui), is usually defined as leakage of urine during movement or activity which puts pressure on the bladder, such as coughing, sneezing, running or heavy lifting. it is reported in most countries that 15% to 40% of women struggle with sui and its severe implications for daily life, including social intera...

in this paper, a general introduction is given, presenting the overactive bladder syndrome (oab) and its impact on the quality of life and economical burden in patients affected. moreover, the anatomy, physiology and histology of the lower urinary tract are discussed, followed by a brief overview on the possible role of prostaglandin (pg) and phosphodiesterase type 5 (pde5) in the urinary bladd...

results during the period from jan 2000 to dec 2011, at our center, 19 children less than eighteen years of age underwent urinary diversion with yang-monti’s catheterizable stoma. the indications for urinary diversion was neuropathic bladder in eight, exstrophy bladder in seven , valve bladder syndrome in three and persistent urethral stricture in one. none of the children found cic difficult d...

REPLY: There is great interest in establishing novel biomarkers for the early detection of renal disease. Although albuminuria is a common biomarker that can be easily measured, evidence suggests that albumin excretion can change independently of glomerular barrier function, and increases in albumin excretion may occur after the damage has occurred or may not be present in all types of kidney d...

BACKGROUND Catheter-Associated Hospital-Acquired Infections (HAI's) are caused by biofilm-forming bacteria. Using a novel approach, we generated anti-infective barrier on catheters by charging them with Nitric Oxide (NO), a naturally-produced gas molecule. NO is slowly released from the catheter upon contact with physiological fluids, and prevents bacterial colonization and biofilm formation on...

BACKGROUND/AIMS Podocytes play an important role in maintaining the glomerular filtration barrier and in formation of the slit diaphragm. Podocyte loss is associated with chronic kidney disease progression, but it is not clear whether urinary podocyte proteins in urine reflect the clinical extent of glomerular damage. We investigated the correlation between the amounts of urinary podocyte prote...

INTRODUCTION Tobramycin is one of the components used for selective decontamination of the digestive tract (SDD), applied to prevent colonization and subsequent infections in critically ill patients. Tobramycin is administered in the oropharynx and gastrointestinal tract and is normally not absorbed. However, critical illness may convey gut barrier failure. The aim of the study was to assess th...

The mammalian bladder maintains high electrochemical gradients between urine and blood, permitting the kidney to modify body chemistries through urinary excretion. To perform this function, the urothelium maintains a tight permeability barrier. When this barrier is damaged, leakage of urine components into the underlying bladder layers results, with symptoms of cystitis. In these studies, we de...

PURPOSE Anxiety may serve as a major barrier to participation in active surveillance. Intolerance of uncertainty, that is the tendency to perceive the potential for negative events as threatening, has been linked to cancer related worry. Accordingly we explored prospectively the relationship of intolerance of uncertainty with anxiety along with other clinical factors among men treated with acti...

The measurement of intestinal permeability is important for diagnoses diseases the gastrointestinal tract, such as Crohn’s disease. gold standard dual sugar absorption test, which measures urinary or blood concentrations two orally administered sugars, a monosaccharide and disaccharide, over period time. lining small intestine allows monosaccharides to cross into bloodstream, but larger disacch...