The cellular fatty acid composition of 20 isolates of Neisseria gonorrhoeae and 21 isolates of N. meningitidis was examined by gas-liquid chromatography. Each isolate of the two species possessed similar fatty acid profiles which were characterized by five major acids, accounting for 80 to 85% of the total. The three most abundant acids in each species were palmitic, palmitoleic, and beta-hydro...

the effect of a selected autochthonous starter culture made up by streptococcus thermophilus, lactobacillus delbrueckii subsp. lactis and lactobacillus helveticus on the microbiological and physicochemical properties of pecorino romano cheese during ripening was investigated. the suitability of the experimental starter culture was tested at industrial scales in cheese-making trials of pecor...

Nucleic acids are macromolecules in cells for storing and transferring genetic information. Moreover, nucleic acids, especially RNAs, can fold into well-defined 3D structures and catalyze biochemical reactions. As ubiquitous biological molecules in all living systems, nucleic acids are important drug targets, and they can also be used in diagnostics and therapeutics. Structural information of n...

Breast cancer is the leading cause of cancer-related death among women worldwide. Tumor-associated macrophages (TAMs) constitute primary component innate immunity in breast tissue. During development new approaches for treatment aimed at editing epigenome TAM, precise methods analysis macrophage metabolome are required to examine effect on metabolism. Our study develop an HPLC-MS/MS-based analy...

Fatty acids of twelve species of cyanobacteria grown under different photoautotrophic conditions were studied and their composition was compared with literature data of many other species. We have come to the conclusion that the lipids of cyanobacteria do not contain fatty acids with a chain longer than 18 carbon atoms. In our opinion, omission of an analytical procedure, i.e. purification of f...

UNLABELLED Identification of correlated amino acids in proteins has been a topic of broad interest in view of its functional implications and importance in protein design. A new set of pair-to-pair (P2P) substitution matrices for amino acids was recently introduced as a useful tool for inferring information on such correlated sites. We present a website developed for automated application of th...

Alkyl chloroformates with methyl, ethyl, and 2-chloroethyl substituents can instantaneously esterify fatty acids under proper reaction conditions. Apart from the formation of the corresponding alkyl esters, even the alkoxycarbonyl esters can be prepared. These derivatives are useful for the analysis of short-chain fatty acids. As alkoxycarbonyl ester, even acetic acid can already be separated f...