نتایج جستجو برای: uva

تعداد نتایج: 3365  

Journal: :Investigative ophthalmology & visual science 2012
Stacy L Littlechild Gage Brummer Yuntao Zhang Gary W Conrad

PURPOSE Laser-assisted in situ keratomileus (LASIK) creates a permanent flap that remains non-attached to the underlying laser-modified stroma. This lack of permanent adhesion is a liability. To immobilize a corneal flap, a protocol using fibrinogen (FIB), riboflavin (RF), and ultraviolet (UVA) light (FIB+RF+UVA) was devised to re-adhere the flap to the stroma. METHODS A model flap was create...

2015
Yuichi Saito Kazuhiro Tsuruma Kenji Ichihara Masamitsu Shimazawa Hideaki Hara

BACKGROUND Exposure to ultraviolet A (UVA) irradiation is the major cause of human skin aging. Suppression of UVA irradiation-induced skin fibroblast cell damage protects the skin against aging. An oxidative stress response transcription factor nuclear factor-(erythroid-derived 2)-related factor 2 (Nrf2) has an important role as a cytoprotective system against oxidative stress in the human skin...

2014
CHI-MING WU YA-LI CHENG YOU-HUA DAI MEI-FEI CHEN CHEE-CHAN WANG

This study aimed to investigate whether α-tocopherol is able to protect keratinocytes against ultraviolet A (UVA) radiation by increasing glutathione (γ-glutamylcysteinylglycine; GSH) levels or decreasing lipid peroxidation and reactive oxygen species (ROS) generation. The cell survival fraction was 43.6% when keratinocytes were irradiated with UVA at a dose of 8 J/cm2. α-Tocopherol was added p...

Journal: :Journal of the American College of Cardiology 2003
Henrik Wiggers Hans Erik Bøtker Peter Søgaard Anne Kaltoft Flemming Hermansen Won Yong Kim Lars Krusell Leif Thuesen

OBJECTIVES We compared catheter-based electromechanical mapping (NOGA system, Biosense-Webster, Haifa, Israel) with positron emission tomography (PET) and single photon emission computed tomography (SPECT) for prediction of reversibly dysfunctional myocardium (RDM) and irreversibly dysfunctional myocardium (IDM) in patients with severe left ventricular dysfunction. Furthermore, we established t...

Journal: :Photochemistry and photobiology 2006
Deeba N Syed Arshi Malik Naghma Hadi Sami Sarfaraz Farrukh Afaq Hasan Mukhtar

UVA is the major portion (90-99%) of solar radiation reaching the surface of the earth and has been described to lead to formation of benign and malignant tumors. UVA-mediated cellular damage occurs primarily through the release of reactive oxygen species and is responsible for immunosuppression, photodermatoses, photoaging and photocarcinogenesis. Pomegranate fruit extract (PFE) possesses stro...

2009
Christian Opländer Christine M. Volkmar Adnana Paunel-Görgülü Ernst E. van Faassen Christian Heiss Malte Kelm Daniel Halmer Manfred Mürtz Norbert Pallua Christoph V. Suschek

Rationale: Human skin contains photolabile nitric oxide derivates like nitrite and S-nitroso thiols, which after UVA irradiation, decompose and lead to the formation of vasoactive NO. Objective: Here, we investigated whether whole body UVA irradiation influences the blood pressure of healthy volunteers because of cutaneous nonenzymatic NO formation. Methods and Results: As detected by chemolumi...

Journal: :Acta dermato-venereologica 2008
Verena Schleyer Oliver Weber Amir Yazdi Frauke Benedix Klaus Dietz Martin Röcken Mark Berneburg

Polymorphic light eruption (PLE), with an overall prevalence of 10-20%, is mainly provoked by ultraviolet A (UVA) (320-400 nm) and to a lesser degree by UVB (280-320 nm). The most effective prophylaxis of PLE, application of UV protection clothing, is not feasible for all sun-exposed areas of the skin and UV-hardening is time-consuming and may be associated with side-effects. Most sunscreens pr...

2016
Nada H. Aldahlawi Sally Hayes David P.S. O'Brart Naomi D. O'Brart Keith M. Meek

The aim of this study was to investigate corneal enzymatic resistance following epithelium off and on riboflavin/UVA cross-linking (CXL). One hundred and fourteen porcine eyes were divided into four non-irradiated control groups and seven CXL groups. The latter comprised; (i) epithelium-off, 0.1% iso-osmolar riboflavin, 9 mW UVA irradiation for 10 min, (ii) disrupted epithelium, 0.1% hypo-osmol...

2014
Xiaoying Guo Po Bian Junting Liang Yichen Wang Luzhi Li Jun Wang Hang Yuan Shaopeng Chen An Xu Lijun Wu

Diesel exhaust has been classified as a potential carcinogen and is associated with various health effects. A previous study showed that the doses for manifesting the mutagenetic effects of diesel exhaust could be reduced when coexposed with ultraviolet-A (UVA) in a cellular system. However, the mechanisms underlying synergistic effects remain to be clarified, especially in an in vivo system. I...

Journal: :The Journal of dermatological treatment 2004
S Valkova A Velkova

BACKGROUND Atopic dermatitis (AD) is a genetically determined pruritic skin disease affecting predominantly young people. The therapy of AD includes mainly corticosteroids (CS), antihistamines and immunosuppressors. CS are known to cause a variety of side effects and attempts have been made to reduce or eliminate their use through alternative methods such as phototherapy (UVA/UVB, UVA(1), UVB 3...

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