background: vitamin d plays a critical role in the regulation of growth and differentiation of squamous epithelium. the pleiotropic effects of 1,25-dihydroxyvitamin d3 [1,25(oh)2d3], include proliferative, pro-apoptotic, and pro-differentiation effects on numerous cell types. although 1,25-dihydroxyvitamin d3 is involved in the regulation and differentiation of epithelium, there is no data in t...

Abstract Introduction Post-menopasual women experience changes in vaginal flora and atrophy that have been associated with declining estrogen levels. These to the microenvironment often lead significant genital pain discomfort during sexual intercourse. Vaginal treats thereby restoring flora, which prevents UTIs improves function post-menopausal women. While is effective, some patients contrain...

Peripheral axons are structurally plastic even in the adult, and altered axon density is implicated in many disorders and pain syndromes. However, mechanisms responsible for peripheral axon remodeling are poorly understood. Physiological plasticity is characteristic of the female reproductive tract: vaginal sensory innervation density is low under high estrogen conditions, such as term pregnanc...

Management considerations Pretreatment evaluation Vasomotor symptoms Urogenital and Vaginal symptoms The role of local vaginal estrogen for treatment of vaginal atrophy in postmenopausal women Progestogen indication Venous thromboembolism Stroke Diabetes mellitus Breast cancer Endometrial cancer Ovarian cancer Colorectal cancer Gallbladder disease Osteoporosis Dementia and cognitive decline Dep...

In a single blind trial, a three day course of butoconazole nitrate cream was compared with a seven day course of miconazole nitrate cream, both applied intravaginally, in treating vaginal candidiasis. They were equally effective. The cure rate for patients treated with butoconazole was 82.8% at the first follow up (a mean of 18.4 days from the beginning of the treatment) and 76.7% at second fo...

Objective: In this study, we aimed at evaluation of the efficacy of Hypericum perforatum and flaxseed on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women Materials and Methods: We searched MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials (RCT) to explore trials that assessed the effectiveness of H. perforatum and flaxseed on hot flash, vagina...

objective: in this study, we aimed at evaluation of the efficacy of hypericum perforatum and flaxseed on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women materials and methods: we searched medline, scopus, and the cochrane central register of controlled trials (rct) to explore trials that assessed the effectiveness of h. perforatum and flaxseed on hot flash, vaginal...

GORSKI, ROGER. Modijcation of ovulatory mechanisms by postnatal administration of estrogen to the rat. Am. J. Physiol. 205(5) 1 842-844. I g63.pThe current studies have demonstrated that the single injection of IOO pug estradiol benzoate to 5-day-old female rats results in permanent sterility. When adult, these rats exhibit anovulatory vaginal cycles in which the stage of vaginal cornification ...