نتایج جستجو برای: variable number tandem repeats

تعداد نتایج: 1444072  

Journal: :The Journal of biological chemistry 2001
K Engelmann S E Baldus F G Hanisch

This study shows for the first time that the tandemly repeated icosapeptide of human MUC1 underlies a genetic sequence polymorphism at three positions (underlined): PDTRPAPGSTAPPAHGVTSA. The concerted replacement DT-->ES (sequence variation 1) and the single replacements P-->Q (sequence variation 2), P-->A (sequence variation 3), and P-->T (sequence variation 4) were identified by sequencing of...

2013
Josephine M Bryant Simon R Harris Julian Parkhill Rodney Dawson Andreas H Diacon Paul van Helden Alex Pym Aziah A Mahayiddin Charoen Chuchottaworn Ian M Sanne Cheryl Louw Martin J Boeree Michael Hoelscher Timothy D McHugh Anna L C Bateson Robert D Hunt Solomon Mwaigwisya Laura Wright Stephen H Gillespie Stephen D Bentley

BACKGROUND Recurrence of tuberculosis after treatment makes management difficult and is a key factor for determining treatment efficacy. Two processes can cause recurrence: relapse of the primary infection or re-infection with an exogenous strain. Although re-infection can and does occur, its importance to tuberculosis epidemiology and its biological basis is still debated. We used whole-genome...

2016
Samin Zamani Mehri Haeili Mohammad Javad Nasiri Abbas Ali Imani Fooladi Sedigheh Javadpour Mohammad Mehdi Feizabadi

Background. Considering that Hormozgan province in Iran (southern part of Iran on the Persian Gulf) is among the areas with high prevalence of MDR-MTB and attracts so many sailors and tourists, genetic diversity of MTB isolates circulating in this part of Iran was evaluated. Pattern of TB transmission was also examined. Methods and Material. A total of 38 isolates of MTB were cultured from TB p...

2012
Svetlana Limborska Andrey Khrunin

The discovery of an anonymous multiallelic locus in 1980 demonstrated for the first time that the human DNA contains hypervariable regions (Wyman & White, 1980). Eight alleles of a polymorphic locus that was not associated with any known gene were identified during the blot hybridization of total human genomic DNA treated with the restrictase EcoRI with a human DNA fragment (16 tbp in length) i...

2014
Jie Liu Chongxiang Tong Jiao Liu Yuan Jiang Xiuqin Zhao Yuanyuan Zhang Haican Liu Bing Lu Kanglin Wan

BACKGROUND Investigations of Mycobacterium tuberculosis genetic diversity in China have indicated a significant regional distribution. The aim of this study was to characterize the genotypes of clinical M. tuberculosis isolates obtained from Gansu, which has a special geographic location in China. METHODOLOGY/PRINCIPAL FINDINGS A total of 467 clinical M. tuberculosis strains isolated in Gansu...

Journal: :BMC Veterinary Research 2006
Florence B Gilbert Angélina Fromageau Jérémy Lamoureux Bernard Poutrel

BACKGROUND Streptococcus uberis is a common cause of bovine mastitis and recommended control measures, based on improved milking practice, teat dipping and antibiotic treatment at drying-off, are poorly efficient against this environmental pathogen. A simple and efficient typing method would be helpful in identifying S.uberis sources, virulent strains and cow to cow transmission. The potential ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید