a:4:{s:10:"Background";s:229:"Although varicocele can be treated, it is considered as one of the most common causes of infertility. This study was performed in order to estimate prevalence of varicocele in adolescents aging 12-14 years in the city of Isfahan.";s:19:"MaterialsAndMethods";s:342:"During this descriptive analytic research, 800 secondary school students who were 12 to 14 years old w...

Male factor infertility often happened in patients with varicocele and genetic disorder. Microsurgical varicocele is the most effective and safe treatment option for male infertility in patients with varicocele. Y chromosome microdeletions and chromosomal abnormalities are the two types of genetic disorder. Now we could use commercial detection kits through PCR amplification of selected regions...

The link between varicocele and infertility was first reported by Celsius in the first century AD, but it was not widely acknowledged until Tulloch and colleagues reported the improvement of sperm parameters in 26 of 30 patients undergoing varicocelectomy. The World Health Organization also reported that varicocele was present in 25% of patients with abnormal sperm parameters and 12% of patient...

Male factor infertility often happened in patients with varicocele and genetic disorder. Microsurgical varicocele is the most effective and safe treatment option for male infertility in patients with varicocele. Y chromosome microdeletions and chromosomal abnormalities are the two types of genetic disorder. Now we could use commercial detection kits through PCR amplification of selected regions...

Backgound: Varicoceles defined as abnormally dilated testicular veins (pampiniform plexus) of in the scrotum and it is found in approximately 15% of the general population and associated with adverse effects on the seminal fluid and fertility. According to size of that blood vessels; the varicocele is divided into clinical that are discovered in physical examination and subclinical that are onl...

OBJECTIVES To determine the possible molecular mechanism for the thickened wall in the internal spermatic vein (ISV) of patients with varicocele, we examined the cadmium (Cd) content and metallothionein (MT) expression in these diseased vessels. Previous studies have shown that Cd might play a role in the etiology of varicocele-associated infertility. MT, a metal-binding protein, protects again...

The glutathione S-transferase (GST) family represents a major group of detoxification and antioxidant enzymes. Studies have shown that high oxidative stress levels are associated with varicocele. The objective of this study was to assess the relationship between GSTM1 and GSTT1 null polymorphisms and varicocele using a study group of 497 varicocele patients and 476 control subjects. A systemati...

Varicocele is the most common and surgically correctible cause of male infertility in men attending to infertility clinics. Infertility affects 15% of all couples and male factor is the primary or contributing cause in 40% to 60% of cases. Varicocele has been shown to cause male infertility in about 15% of infertile couples. Molecular mechanisms responsible from varicocele induced testicular dy...

Oxidative stress is known as the leading factor responsible for varicocele-related infertility and for that reason, many antioxidant therapies have been proposed. Considering that, we evaluated the reproductive outcomes and fertility of varicocelized rats and the impact of chrysin within these parameters. The animals were allocated into three groups: sham (control), varicocele treated via gavag...