BACKGROUND Diabetes-induced vascular dysfunction may arise from reduced nitric oxide (NO) availability, following interaction with superoxide to form peroxynitrite. Peroxynitrite can induce formation of 3-nitrotyrosine-modified proteins. RhoA/ROCK signaling is also involved in diabetes-induced vascular dysfunction. The study aimed to investigate possible links between Rho/ROCK signaling, hyperg...

BACKGROUND Persistent infant stridor, seal-like cough, and difficulty feeding can be the initial signs of right aortic arch with an aberrant left subclavian artery. This congenital cardiovascular abnormality results in the development of a vascular ring that encircles the trachea and esophagus. METHODS A case report is presented that describes the evaluation and care of a 6-week-old male infa...

Abstract Pulmonary agenesis is a rare malformation associated with congenital heart disease and may lead to life-threatening condition death without pre-planned surgical medical support. We report an unusual case of unilateral pulmonary in combination total anomalous venous connection, complete vascular ring, retroaortic, retroesophageal innominate vein, secondary atrial septal defect, which wa...

Report of a surgical treatment for vascular ring (right aortic arch and the anomalous origin of the left subclavian artery) related to Kommerell diverticulum with resection of the ligamentum arteriosum (ductus arteriosus), suture of the Kommerell diverticulum, and reimplantation of left subclavian artery in the ipsilateral carotid artery through left thoracotomy in a 13-year-old female.

Through the actions of its main biological peptide, angiotensin (Ang) II, the renin–angiotensin system (RAS) has been implicated in atherosclerosis.1,2 The proatherogenic effect of Ang II may involve a variety of proinflammatory mechanisms that are largely independent from its effect on blood pressure.1 Ang II promotes monocyte and endothelial cell activation, as well as leukocyte recruitment a...