نتایج جستجو برای: vector vaccine

تعداد نتایج: 302499  

Journal: :Journal of immunology 2006
Yucheng Tang Hakan Akbulut Jonathan Maynard Line Petersen Xiangming Fang Wei-Wei Zhang Xiaoqin Xia James Koziol Phyllis-Jean Linton Albert Deisseroth

We showed that the Ad-sig-TAA/ecdCD40L vaccine induces a tumor suppressive immune response to the hMUC-1 and rH2N tumor-associated self Ags (TAA) and to the Annexin A1 tumor vascular Ag, even in mice in which anergy exists to these Ags. When the TAA/ecdCD40L protein is given s.c. as a boost following the Ad-sig-TAA/ecdCD40L vector, the levels of the TAA-specific CD8 T cells and Abs increase dra...

Journal: :The Journal of Pediatric Pharmacology and Therapeutics 2007

2011
James B Whitney Saied Mirshahidi So-Yon Lim Lauren Goins Chris C Ibegbu Daniel C Anderson Richard B Raybourne Fred R Frankel Judy Lieberman Ruth M Ruprecht

BACKGROUND We have evaluated an attenuated Listeria monocytogenes (Lm) candidate vaccine vector in nonhuman primates using a delivery regimen relying solely on oral vaccination. We sought to determine the impact of prior Lm vector exposure on the development of new immune responses against HIV antigens. FINDINGS Two groups of rhesus macaques one Lm naive, the other having documented prior Lm ...

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