The mode of ventilation used during awake extubation has not previously been studied. We conducted a randomised controlled trial comparing spontaneous respiration, intermittent positive pressure ventilation, and pressure support ventilation (each n = 13) for incidence and severity of peri-extubation complications following routine elective surgery. We found the severity of peri-extubation cough...

OBJECTIVE To determine the efficacy of chest compression accompanied by a 10-cmH2O increase in baseline inspiratory pressure on pressure support ventilation, in comparison with that of aspiration alone, in removing secretions, normalizing hemodynamics, and improving respiratory mechanics in patients on mechanical ventilation. METHODS This was a randomized crossover clinical trial involving pa...

in recent years, biosurfactants due to wide applications in chemical, petroleum, food andpharmaceutical industries, have been widely considered by researchers. biosurfactants are produced by aseries of microorganisms, so it is important to screen culture medium and operating conditions in miniaturized bioreactors prior to scaling up to large bioreactors.in this study, using a kind of miniaturiz...

Introduction Pressure-support ventilation improves lung mechanics, blood gas exchange, hemodynamics, and work of breathing (WOB) in mild acute respiratory distress syndrome (ARDS) [1,2]. Nevertheless, those beneficial effects could be dependent of positive end-expiratory pressure (PEEP) applied during mechanical ventilation. So far, no study has compared pressure-support ventilation (PSV) with ...

BACKGROUND Preservation of spontaneous breathing (SB) is sometimes debated because it has potentially both negative and positive effects on lung injury in comparison with fully controlled mechanical ventilation (CMV). We wanted (1) to verify in mechanically ventilated patients if the change in transpulmonary pressure was similar between pressure support ventilation (PSV) and CMV for a similar t...

The aim of this study was to investigate the effects of different pressurization rates during pressure support ventilation on breathing pattern, work of breathing, gas exchange and patient comfort in patients with acute lung injury. The pressurization rate modifies the initial pressure ramp by changing the initial peak flow rate: the increase in pressurization rate is associated with a decrease...

BACKGROUND AND OBJECTIVES Pressure controlled ventilation (PCV) is available in anesthesia machines, but there are no studies on its use during CO2 pneumoperitoneum (CPP). This study aimed at evaluating pressure-controlled ventilation and hemodynamic and ventilatory changes during CPP, as compared to conventional volume controlled ventilation (VCV). METHODS This study involved 16 dogs anesthe...

Because intubation can potentially become a lengthy procedure, the risk of arterial oxygen (O2) desaturation during intubation must be considered. Preoxygenation should be routine, as oxygen reserves are not always sufficient to cover the duration of intubation. Three minutes of spontaneous breathing at FiO2=1 allows denitrogenation with FAO2 close to 95% in patients with normal lung function. ...

Introduction Management of mechanical ventilation is complex. Guidelines to aid in managing settings may fail to adapt general goals to the individual patient physiology. The Beacon Caresystem (Mermaid Care, Denmark) is a commercial version of a physiological-model based system for advising on mechanical ventilation (1). Mathematical models are tuned to patient measurements allowing advice to b...

expiratory pressure; Phihigh airway pressure level with BiPAP; Plolow airway pressure level with BiPAP; PSVpressure support ventilation; PVRlpulmonary vascular resistance index; RVEDVright ventricular enddiastolic volume; RVEFright ventricular ejection fraction; RVESVright ventricular end-systolic volume; RVPSPright ventricular peak systolic pressure; RVSV right ventricular stroke volume; RVSWI...