The muscarinic receptor was studied in vivo in the human heart by a noninvasive method, positron emission tomography (PET). The study showed that the binding sites of 11C-labeled methiodide quinuclidinyl benzilate [( 11C]-MQNB), a muscarinic antagonist, were mainly distributed in the ventricular septum (98 pmol/cm3 of heart) and in the left ventricular wall (89 pmol/cm3), while the atria were n...

Being able to view the morphological details of the heart malformation in any patient with the diagnosis of atrioventricular septal defect (AVSD) is invaluable in surgical planning, especially in the current era of modified 1-patch versus 2-patch techniques. Real-time 3-dimensional transesophageal echocardiography (RT 3D TEE) is a recently developed technique that allows real-time high-quality ...

OBJECTIVE Transmural heterogeneity in the ventricular free wall, enhanced by the midmyocardial long action potential duration (APD) of M cells, plays an important role in the arrhythmogenesis of long QT syndrome. Although we observed dynamic expression of M cell phenotypes in the canine ventricular free wall, it is still unclear whether similar phenomena are present in the interventricular sept...

Aim of the work To study extent right ventricular (RV) dysfunction in ischemic patients after coronary artery bypass grafting (CABG). Patients and methods RV function was studied preoperatively followed for 1 month postoperatively 40 who were scheduled elective surgery other controls. We evaluated by tissue Doppler tricuspid annulus basal septum, annular plane systolic excursion, dimensions. Bo...

Over the past 2 decades several investigators (1-4) have attempted to demonstrate with a variety of methodologies that the morphologically right ventricle in p miens with either pulmonary atresia or critical pulmonary stenosis can grow after surgical intervention . That growth should occur in a morphologically right ventricle whose dimensions are nearly normal or in an occasional patient with a...