نتایج جستجو برای: verifynow
تعداد نتایج: 293 فیلتر نتایج به سال:
OBJECTIVES The objective was to evaluate the pharmacodynamic response of switching patients on maintenance phase clopidogrel therapy after an acute coronary syndrome (ACS) to prasugrel. BACKGROUND Prasugrel P2Y(12) receptor blockade is associated with greater pharmacodynamic platelet inhibition and reduction of ischemic complications compared with that of clopidogrel in ACS patients undergoin...
BACKGROUND The clinical impact of platelet aggregation assessed by point-of-care assays is unknown. We sought to evaluate whether high residual platelet reactivity (RPR) to ADP during clopidogrel therapy, measured by a point-of-care assay, predicts adverse clinical events in acute coronary syndrome patients undergoing percutaneous coronary intervention. METHODS AND RESULTS We used the VerifyN...
and its contents are solely the responsibility of the authors and do not necessarily represent the official view of NCRR or NIH. He is participating in ongoing clinical trials of tolvaptan for the treatment of autosomal dominant polycystic kidney disease sponsored by Otsuka Pharmaceutical Development and Commercialization Inc, and is a consultant to Forest Research Institute Inc and Primrose Th...
Abstract Objectives This study aimed to determine the prognostic value of serial measurement platelet reactivity (PR) using VerifyNow, P2Y12 reaction unit (PRU) assay following percutaneous coronary intervention (PCI) during antiplatelet therapy. Background On-treatment PR changes over time, but measurements has not been defined. Methods We enrolled 3204 patients who had PCI and were measured a...
Abstract Objectives To rule out a drug-drug interaction (DDI) among cangrelor-treated patients who have been pre-treated with ticagrelor. Background There are no studies specifically designed to DDI when cangrelor is used Methods In this prospective, randomized, double-blind, placebo-controlled, cross-over, pharmacokinetic (PK) and pharmacodynamic (PD) study, coronary artery disease (n = 20) we...
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