Rhizomes of Boesenbergia pandurata (Roxb.) Schlecht have been reported to contain active compounds with anticancer properties. This research was carried out to examine anti-proliferative and apoptotic induction against HeLa and Vero cells-line. Dried powder of B. pandurata rhizomes was extracted by a maceration method using 90% ethanol. Cytotoxic assays to determine IC50 and anti-proliferative ...

A proteomic approach was used to investigate the dynamic cellular host cell response induced by influenza virus infection in two different vaccine production cell lines, MDCK and Vero. For identification of proteins possibly involved in global host cell response mechanisms and virus-host cell interactions in these producer cell lines, quantitative 2-D DIGE and nanoHPLC-nanoESI-MS/MS analysis we...

Siti SYarifaH mm, nurHanan mY, muHd Haffiz J, moHd ilHam a, GetHa K, aSiaH o, norHaYati i, lili SaHira H & anee SurYani S. 2011. Potential anticancer compound from Cerbera odollam. The cytotoxicity of the leaf of Cerbera odollam was investigated against two breast cancer cell lines (T47D and MCF7), two ovarian cancer cell lines (SKOV3 and CaOV3) and a normal (Vero) cell line. The crude methanol...

Zika virus (ZIKV) has infected thousands of Brazilian people and spread to other American countries since 2015. The introduction of ZIKV brought a strong impact to public health in Brazil. It is of utmost importance to identify a susceptible cell line that will enable the isolation and identification of the virus from patient samples, viral mass production, and testing of drug and vaccine candi...

A number of epidemiological studies have shown human metapneumovirus (hMPV) to be one of the most important viral agents associated with acute respiratory infections in humans. However, due to the difficulty in growing the virus, all epidemiological studies of hMPV infection have been performed on the basis of the molecular method. Thus, the development of a cell line suitable for the isolation...

Purpose: The research paper studies the in vitro anti-candida activity and cytotoxic effects of Aloe vera (Linn) leaves extract against melanoma normal cell lines. Subjects Methods: traditional Soxhlet apparatus was used to prepare crude plant using organic solvents. agar well diffusion method explore anti-candida, MTT assay assess activity. Results: With IC50 values 250 g/ml more than 1000 g/m...

Five known compounds, four triterpenoids [(lup-20(30)-ene-3 ,29-diol (1), lup-20(29)-ene-30-hydroxy-3one-(2), – taraxastanonol 3, -sitosterol 4] and 4’ –Omethylepigallocatechin 5 were isolated from Elaeodendron transvaalense bark ethanol extract. This plant is traditionally used in Southern Africa for the treatment of various ailments including sexually associated diseases. Cytotoxicity of the ...

BACKGROUND Cancer is a leading cause of death world-wide, with approximately 17.5 million new cases and 8.7 million cancer related deaths in 2015. The problems of poor selectivity and severe side effects of the available anticancer drugs, have demanded the need for the development of safer and more effective chemotherapeutic agents. The present study was aimed at determining the cytotoxicities ...