Ventriculocisternal perfusion (VCP) of artificial cerebrospinal fluid (CSF) was performed in pentobarbital-anesthetized dogs. Renal function was studied in protocols consisting of a 1-h experimental period in which the animals received either CSF with an elevated sodium concentration (300 mM, high Na) via VCP or antidiuretic hormone (ADH) intravenously, bracketed by 1-h control and recovery per...

Valosin-containing protein (VCP), also called p97, is a AAA+ ATPase that has been shown to be involved in endoplasmic reticulum-associated protein degradation (ERAD), mitochondria quality control and vesicle transport. We and others have previously found that disruption of VCP is sufficient to cause endoplasmic reticulum (ER) stress. We observed that induction of ER stress either following siRN...

The 28.6 kDa vaccinia virus complement control protein (VCP) is an inhibitor of the complement system and has therapeutic potential. It is composed of four domains or modules and is a homologue of complement receptor 1 (CR1) and other mammalian regulators of complement activation. A key aspect to structure-function relationships in these proteins is the extent of intramolecular module-module in...

BACKGROUND The ubiquitin proteasome system (UPS) is a key player in regulating many cellular processes via proteasomal degradation of ubiquitinated proteins. Recently published data show that Jab1/CSN5 interacts with p97/VCP and controls the ubiquitination status of proteins bound to p97/VCP in mouse and human cells. However, coexpression of p97/VCP and Jab1/CSN5 in the developing rat testis an...

The leaf area density (LAD) within a tree canopy is very important for the understanding and modeling of photosynthetic studies of the tree. Terrestrial light detection and ranging (LiDAR) has been applied to obtain the three-dimensional structural properties of vegetation and estimate the LAD. However, there is concern about the efficiency of available approaches. Thus, the objective of this s...

Vaccinia virus complement control protein (VCP) is a virulence determinant of vaccinia virus that helps protect the virus from the complement attack of the host. To characterize the interaction of VCP with C3 and C4 and understand the mechanism by which VCP inactivates complement, we have expressed VCP in a yeast expression system and compared the biologic activity of the purified protein to th...

Given an undirected graph, the Vertex Coloring Problem (VCP) consists of assigning a color to each vertex of the graph in such a way that two adjacent vertices do not share the same color and the total number of colors is minimized. DSATUR-based Branch-and-Bound algorithm (DSATUR) is an effective exact algorithm for the VCP. One of its main drawback is that a lower bound is computed only once a...

Abstract
 Aim: The 97-kDa Valosin-containing protein has important functions in proteolysis. Although the expression of p97 / VCP been studied many types cells and tissues, localization at cellular level developing mouse pancreas liver not determined. Therefore, aim our study was investigate immuolocalization p97/VCP rat fetal postnatal pancreas. 
 Material Methods: from fetal, (1, 5,...

We examine the complexity of testing di erent program constructs. We do this by de ning a measure of testing complexity known as VCP-dimension, which is similar to the Vapnik-Chervonenkis dimension, and applying it to classes of programs, where all programs in a class share the same syntactic structure. VCP-dimension gives bounds on the number of test points needed to determine that a program i...

C3 and C3b, the components central to the complement activation, also play a damaging role in several inflammatory disorders. Vaccinia virus complement control protein (VCP) and curcumin (Cur) are natural compounds with different biological origins reported to regulate complement activation. However, both VCP and Cur have not been investigated for their interaction with the third component (C3)...