Background Vessel wall inflammation plays a key role in the initiation and progression of atherosclerosis, from endothelial injury to remodeling and plaque formation. Cardiovascular (CV) magnetic resonance (CMR) provides noninvasive visualization and characterization of arterial remodeling both in the great vessels, and also the coronary arteries. Contrast-enhanced inversion-recovery (CEIR) pre...

Coronary magnetic resonance angiography (CMRA) allows a noninvasive assessment of the coronary anatomy without exposing the patients to radiation. It is also superior to coronary computed tomography angiography (CCTA) for the evaluation of luminal narrowing in heavily calcified coronary segments. We report a case with triple-vessel disease, but it could not be accurately assessed by CCTA becaus...

OBJECTIVE To determine the correlation of cardiac troponin I (cTnI) 10 folds upper limit of normal (ULN) and extent of coronary artery disease (CAD) in Non-ST-elevation myocardial infarction (NSTEMI). METHODS A cross-sectional study was conducted on 230 consecutive NSTEMI patients admitted in Tabba Heart Institute, Karachi between April to December 2008. cTnI was measured using MEIA method. A...

Childhood Takayasu arteritis is one of the most common vasculitis in paediatric age group. It predominantly involves greater vessels such as aorta and its branches, leading to granulomatous inflammation. The process inflammation gives rise symptoms based on thrombotic or aneurysmal phenomena. This a case report 11-year-old girl diagnosed an urban tertiary care centre India with childhood arteri...

Granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a rare immunological small vessel disease which usually affects respiratory tract and kidneys. However, salivary gland involvement in GPA primary manifestation. We report case of the presentation submandibular involvement. A 48-year-old female patient presented swelling skin defect that lasted for 1 month. Al...

OBJECTIVE To evaluate the outcomes of major vessel reconstruction as part of surgery to remove sarcomas. DESIGN Retrospective review. SETTING Tertiary academic medical center. PATIENTS Fourteen patients (10 female) with retroperitoneal or extremity sarcomas and major blood vessel involvement who underwent surgery to remove the tumor and had blood vessel reconstruction between 2003 and 200...

BACKGROUND/AIMS Gastrointestinal involvement in vasculitis may result in life-threatening complications. However, its variable clinical presentations and endoscopic features, and the rarity of the disease, often result in delayed diagnosis. METHODS Clinical characteristics, endoscopic features, and histopathological findings were reviewed from medical records. RESULTS Of 6,477 patients with...

Allergic granulomatous angiitis (Churg-Strauss syndrome) is a variant of systemic vasculitis characterized by pulmonary and systemic small vessel vasculitis, extra-vascular granulomas and eosinophilia. Clinical features include presence of asthma and/or allergic rhinitis with constitutional symptoms such as fever and weight loss. Multisystem involvement includes pulmonary infiltrations, m...