Adenovirus protein VII is the major component of the viral nucleoprotein core. It is a highly basic nonspecific DNA-binding protein that condenses viral DNA inside the capsid. We have investigated the fate and function of protein VII during infection. "Input" protein VII persisted in the nucleus throughout early phase and the beginning of DNA replication. Chromatin immunoprecipitation revealed ...

Discrete Sine Transforms of types VI and VII (DST-VI/VII) have recently received considerable interest in video coding. In particular, it was shown that DST-VII offers good approximation for KLT of residual signals produced by spatial (Intra) prediction process. In this paper, we offer an additional argument for use of such transforms by showing that they allow fast computation. Specifically, w...

Factor VII deficiency is characterized by epistaxis, bruising, hemarthrosis, menorrhagia, gastrointestinal bleeding, hematuria, and intracranial hemorrhage during infancy. Causes of acquired factor VII deficiency include liver disease, Vitamin K deficiency, and warfarin administration. Congenital factor VII deficiency is an autosomal recessive disorder, with the homozygotes having a severe defi...

The ocean is a rich resource of flora, fauna, food, and biological products. We found a wild-type bacterial strain, Pseudoalteromonas sp. M2, from marine water and isolated various secondary metabolites. Pseudane-VII is a compound isolated from the Pseudoalteromonas sp. M2 metabolite that possesses anti-melanogenic activity. Inflammation is a response of the innate immune system to microbial in...

The organic-inorganic hybrid material of polyaniline/titanium(IV) (PANI/Ti(HPO4)2) was synthesized by an oxidative polymerization reaction. The PANI/Ti(HPO4)2 was applied to remove Re(VII). The size of Ti(HPO4)2 nanoplates has no obvious effect on the sorption capacity. The effects of various environmental factors (such as pH, extra anions (NO3(-) and MO4(2-)) and temperature) on Re(VII) sorpti...

Factor VII circulates as a single chain inactive zymogen (10 nmol/L) and a trace ( approximately 10-100 pmol/L) circulates as the 2-chain form, factor VIIa. Factor VII and factor VIIa were studied in a coagulation model using plasma concentrations of purified coagulation factors with reactions initiated with relipidated tissue factor (TF). Factor VII (10 nmol/L) extended the lag phase of thromb...

..................................................................................... III POPULÄRVETENSKAPLIG SAMMANFATTNING ..........................V LIST OF PAPERS ........................................................................... VII ABBREVIATIONS ............................................................................ IX TABLE OF CONTENTS ........................................

......................................................................................................... I PREFACE .......................................................................................................... III APPENDED PAPERS AND CONTRIBUTIONS ........................................... V ACKNOWLEDGEMENTS ............................................................................

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* Acknowledgements. This paper was presented as an invited lecture in the VII Jornadas de Economia Internacional -Málaga, June 2001and the Workshop on Economic Decisions Pamplona, June 2002. I wish to thank Antonia Díaz for the conversation that led to this paper and to Michele Boldrin, Klaus Desmet, Ricardo Mora, Georges Siotis and Jaume Ventura for helpful comments and to CICYT for support un...