Leishmania infantum is the obligatory intracellular parasite of mammalian macrophages and causes zoonotic visceral leishmaniasis (ZVL). The presence of infected dogs as the main reservoir host of ZVL is regarded as the most important potential risk for human infection. Thus the prevention of canine visceral leishmaniasis (CVL) is essential to stop the current increase of the Mediterranean visce...

BACKGROUND In this paper we study the distribution of leukocyte populations and of cytokine-producing cells in the spleen of a patient with visceral leishmaniasis resistant to clinical treatment. It is the first attempt to compare the distribution of leukocyte populations and cytokine-producing cells in the splenic compartments of a patient with visceral leishmaniasis with those observed in pat...

  Kale- azar is known as an endemic doses in some areas of Cars province ( in South) and Ardabil province ( in North- west) of Iran. In other provinces the disease has been reported, mostly, in sporadic from. However since 1949 when the first case of kale- azar was reported in Mazandaran province, to  the end of 1993 more than 4300 cases had been diagnosed in at least 113 cities and districts....

background: visceral leishmaniasis (vl) is an endemic disease in some parts of iran. many techniques have been used for diagnosis of vl, among which the urine based la-tex agglutination test (katex) is a promising one. objective: to compare three diag-nostic tests of vl including katex, elisa and direct agglutination test (dat) in vl patients and healthy controls in the south west of iran. meth...

Forty-one naturally infected dogs with visceral leishmaniasis from an urban area of Corumbá (Mato Grosso do Sul-BRAZIL) were studied and three types of lung involvement due to visceral leishmaniasis were characterized; a cellular, a cellular-fibrotic and a fibrotic type. These types seem to represent a sequential evolutive proce'as. Visceral leishmaniasis frequently causes an interstitial pneu ...

Leishmaniasis is a neglected tropical disease infecting world’s poorest population in over 90 countries throughout Asia, Africa, the Middle East, and Central South Africa. An underestimated 700,000 to one million new cases occur annually. refers spectrum of diseases caused by parasite, Leishmania, transmitted bite infected sandflies. Of three major syndromes (cutaneous, mucosal visceral) leishm...

visceral leishmaniasis (vl) is a zoonotic disease caused by leishmania species. dogs are considered to be the main reservoir of vl. a number of methods and antigen-based assays are used for the diagnosis of leishmaniasis. however, currently available methods are mainly based on direct examination of tissues for the presence of parasites, which is highly invasive. a variety of serological tests ...

background: previous studies revealed that selectins play key roles in homing of immune cells to inflamed tissues and lymphatic organs. l-selectins are expressed on immune cells and interact with p and e selectins to homing to the tissues, hence, the polymorphisms within the gene of l-selectins may are associated with alteration in its expression. thus, the current cross-sectional analytical st...

BACKGROUND Visceral Leishmaniasis coinfection with HIV/AIDS has emerged as a series of disease pattern. It most often results in unfavorable responses to treatment, frequent relapses, and deaths. Scarce data is available regarding the prevalence of HIV and associated factors among Visceral Leishmaniasis coinfected patients. This study sought to determine the prevalence of HIV and associated fac...

Mucocutaneous leishmaniasis, which mostly occurs in the New World, is mainly associated with Leishmania braziliensis and to a lesser degree L. panamensis and L. amazonensis infections. Primary mucosal leishmaniasis is very rare in Iran in spite of high prevalence of cutaneous and visceral leishmanisis. A nine-year-old boy had cutaneous leishmaniaisis for five years involving the left side of hi...