PURPOSE To describe a technique of vitreous base visualisation through trans-scleral illumination using a standard 25-gauge light probe. METHODS All vitrectomies are performed using 25-gauge+ instruments and valved trocars. A non-contact viewing system is used to visualise the retina. After core vitrectomy and the necessary additional procedures, triamcinolone acetonide (Kenacort) is injected...

PURPOSE When human retinal pigment epithelial (RPE) cells come in contact with vitreous, they undergo changes in gene expression that include inflammatory and anti-oxidant responses. The effects of vitreous on expression of heme oxygenase-1 (HO-1), metallothionein (MT) -1a and -2a, and c-fos were investigated. Activator protein-1 (AP-1) binding sites are located in the promoter region of HO-1 a...

PURPOSE To investigate the vitreous findings in patients with cicatricial retinopathy of prematurity (ROP) who underwent retinal cryopexy and/or photocoagulation during the acute phase of the disease. METHODS Vitreous findings were evaluated in 15 patients (29 eyes) with cicatricial ROP by slit-lamp biomicroscopy and indirect ophthalmoscopy. RESULTS The ocular examination revealed that all ...

PURPOSE To develop an automated method for quantifying vitreous signal intensity on optical coherence tomography (OCT), with particular application for use in the assessment of vitreous inflammation. METHODS This retrospective, observational case-control series comprised 30 patients (30 eyes), with vitreous haze secondary to intermediate, posterior, or panuveitis; 12 patients (12 eyes) with u...

PURPOSE To investigate the vitreous and plasma levels of vascular endothelial growth factor (VEGF) in patients with proliferative diabetic retinopathy (PDR) and to determine whether they predict a disease prognosis after primary vitrectomy. METHODS Fifty patients (50 eyes) with PDR who underwent pars plana vitrectomy (PPV) and 56 healthy controls (56 eyes) were enrolled in this retrospective ...

For the first time, vitreous oxygen tension in the human vitreous body was measured using a polarographic oxygen electrode during vitreous surgery. The same method was used in a rabbit experimental model. In the human eye, the mean oxygen tensions of the anterior peripheral vitreous body, central vitreous body and posterior vitreous body were 16.7 +/- 3.7 mm Hg (mean +/- 1 SD), 15.9 +/- 2.8 mmH...

Background: Anterior vitreous incarceration is a condition in which vitreous prolapses into the anterior chamber and passes through a microscopic wound at an incisional site. The condition can be identified as a vitreous strand leading to the wound site during slit lamp examination. If the vitreous strand penetrates through all the corneal layers on to the extraocular surface it becomes vitreou...

PURPOSE To evaluate the influence of sclerotomy use during vitrectomy (vitreous cutter, illumination probe, or infusion-line entrance) on postoperative vitreous incarceration using an experimental model of vitrectomized eye. MATERIALS AND METHODS Experimental, randomized, and observer-masked study in which 23-gauge transconjunctival sutureless vitrectomy was performed in cadaveric pig eyes. P...