To examine the relationship between end-expiratory lung volume and respiratory muscle work during acute bronchoconstriction, we measured the work of breathing in nine asthmatic subjects, in whom bronchoconstriction was induced with histamine aerosol. When the forced expiratory volume in one second (FEV1) fell below 60% of the control value, work was measured at the spontaneously hyperinflated l...

Vapor-liquid-solid (VLS) is a well-established process in catalyst-guided growth of nanowires. The catalyst particle is generally believed to be in liquid state during growth, and it is the site for adsorbing incoming molecules; the crystalline structure of the catalyst may not have any influence on the structure of the grown one-dimensional nanostructures. In this paper, using tin particle gui...

In recent years, there has been rapid urbanization worldwide, resulting in both benefits and problems. Sustainable urbanization has become an important aspect in promoting sustainable development. Existing studies have introduced various methodologies to guide urbanization towards sustainable practices. The application of these methods has contributed to improving urban sustainability. To furth...

Software-managed local stores have proven to be more efficient than hardware-managed caches for some important applications, yet their use has been mostly confined to embedded systems that run a small set of applications in a limited runtime environment. Local stores are problematic in general-purpose systems because they add to process state on context switches, and because they require fast d...

In the current study, we investigated the nature and role of CD44 variant isoforms involved in endothelial cell (EC) injury and tumor cell cytotoxicity mediated by IL-2-activated killer (LAK) cells. Treatment of CD44 wild-type lymphocytes with IL-2 led to increased gene expression of CD44 v6 and v7 variant isoforms and to significant induction of vascular leak syndrome (VLS). CD44v6-v7 knockout...

Vascular leak syndrome (VLS) was originally found to be a major dose-limiting toxicity in humans with cancer treated with several immunotoxins (ITs) containing ricin A chain or blocked ricin. Recently, VLS has also been observed in patients treated with an IT containing the murine monoclonal antibody (MAb) B3 coupled to LysPE38, a recombinant truncated form of Pseudomonas exotoxin (PE) A. Antib...

AIM To evaluate the larynx involvement in patients with rheumatoid arthritis (RA) in a clinical setting and correlate with the different clinical features related to more aggressive disease. METHODS Cross-sectional study including 36 consecutive patients with RA. Reflux symptoms were evaluated by the Reflux Symptom Index (RSI) and vocal cord impairment by the Voice Handicap Index-10 (VHI-10)....

Using the two-loop approximation of chiral perturbation theory, we calculate the momentum and density dependent isovector nuclear spin-orbit strength Vls(p, kf ). This quantity is derived from the spin-dependent part of the interaction energy Σspin = i 2 ~σ · (~q × ~ p )[Uls(p, kf ) − Vls(p, kf )τ3δ] of a nucleon scattering off weakly inhomogeneous isospinasymmetric nuclear matter. We find that...