Neurofibromatosis type 1 (NF-1), first described by Von Recklinghausen (1882), is an autosomal dominant disease caused a spectrum of mutations in NF-1 gene. We reported case giant facial neurofibromas 26 years old male patient without family history neurofibromatosis 1. Features typical neurofibroma, including enlarged nerve fascicle composed elongated nuclei and scant cytoplasmic cells, were i...