Wobble base pairs are critical in various physiological functions and have been linked to local structural perturbations in double-helical structures of nucleic acids. We report a 1.38-Å resolution crystal structure of an antiparallel octadecamer RNA double helix in overall A conformation, which includes a unique, central stretch of six consecutive wobble base pairs (W helix) with two G·U and f...

Compatible living donor/recipient pair participation (CPP) in kidney exchange (KE) transplantation may substantially increase transplant volumes and significantly mitigate the O blood group donor shortage in KE. Initial ethical analysis did not support CPP for two primary reasons: (1) KE would be "unbalanced," and (2) the possibility of undue influence experienced by the compatible pair living ...

Interrupted aging in the two-dimensional Ising spin glass model with Gaus-sian couplings is established and investigated via extensive Monte-Carlo simulations. The spin autocorrelation function scales with t/τ (t w), where t w is the waiting time and τ is equal to t w for waiting times smaller than the equilibration time τ eq. The spatial correlations scale with r/ξ(t w), where the correlation ...

The paper discusses the development of an IBM PC based tool, for calculating train braking distances for various train classes on a rail network. There is discussion on current industry practice and the limitations of that practice, the concept of the tool itself, including the assumptions made, the strategy adopted to minimise the risk of incorrect calculations, and the results of adopting tha...

A further commercially available encryption package for the IBM PC is analysed, and a simple breaking program is described.

This is a paper in a series to study vertex algebra-like structures arising from various algebras including quantum affine algebras and Yangians. In this paper, we study notions of ~-adic nonlocal vertex algebra and ~-adic (weak) quantum vertex algebra, slightly generalizing Etingof-Kazhdan’s notion of quantum vertex operator algebra. For any topologically free C[[~]]-module W , we study ~-adic...

Partial words are sequences over a finite alphabet that may contain wildcard symbols, called holes, which match or are compatible with all letters; partial words without holes are said to be full words (or simply words). Given an infinite partial word w, the number of distinct full words over the alphabet that are compatible with factors of w of length n, called subwords of w, refers to a measu...

The stable roommates problem with payments has as input a graph G = (V,E) with an edge weighting w : E → R≥0 and the problem is to find a stable solution. A solution is a matching M with a vector p ∈ R≥0 that satisfies pu + pv = w(uv) for all uv ∈ M and pu = 0 for all u unmatched in M . A solution is stable if it prevents blocking pairs, i.e., pairs of adjacent vertices u and v with pu + pv < w...