background: it is becoming apparent that although inhibition of cholinesterase plays a key role in organophosphate (op) toxicity, other factors are also important. one of the contributing factors for severity of op poisoning is electrolyte imbalances such as hypokalemia. this study was aimed at evaluating the value of hypokalemia in association with plasma cholinesterase (pche) levels in predic...

congenital mullerian abnormalities, particularly the septate uterus, may result in recurrent abortion, premature labor and infertility. the purpose of this study is to report the surgical and reproductive outcome in two groups of patients who underwent hysteroscopic metroplasty (hmp). between aug. 1993 and march 1998,76 women underwent hmp in shiraz university of medical sciences' affiliat...

Osteopetrotic (op/op) mice are characterized by an autosomal recessive inactivating mutation resulting in the absence of biologically active colony-stimulating factor-1 (CSF-1). Consequently, young op/op mice have a severe deficiency of macrophages and osteoclasts resulting in excessive bone formation, occlusion of the marrow cavity, and reduced marrow hematopoietic activity. Recently, we showe...

Abstract This paper examines the use of laughter as redemption in Samuel Beckett’s Waiting for Godot and Endgame . By acknowledging somatic life characters, humour problematises un-embodied philosophies life. Challenging Hugh Kenner’s claim that is not redemptive because dryness repetitions involved, it argued foregrounding fragility vulnerability a way expressing deeply humane While highlighti...

Previous studies of osteopetrotic (op) mice lacking macrophage colony-stimulating factor (M-CSF) have revealed an inhibition of atherosclerosis development in the apolipoprotein E (apo E)-deficient model and in a diet-induced model. Using LDL receptor-deficient mice, we now show that atheroma development depends on M-CSF concentration, as not only did homozygous osteopetrotic (op/op) mice have ...

OBJECTIVE Angiotensin (Ang) II-induced vascular damage may be partially mediated by reactive oxygen species generation and inflammation. Homozygous osteopetrotic mice (Op/Op), deficient in macrophage colony-stimulating factor (m-CSF), exhibit reduced inflammation. We therefore investigated Ang II effects on vascular structure, function, and oxidant stress generation in this model. METHODS AND...

Compared with normal littermates, the op/op mice had very few macrophages in the peritoneal cavity and severely reduced numbers of monocytes in the peripheral blood. Moreover, osteopetrotic animals demonstrated an altered distribution of hemopoietic tissue with a 10-fold decrease in the number of marrow cells. Liver hemopoiesis persisted in 4-wk-old mice as evidenced by the presence of hemopoie...

Organophosphate resistant and susceptible tick larvae from laboratory strains of the southern cattle tick, Rhipicephalus (Boophilus) microplus were exposed to low doses of the organophosphate (OP) acaricide, coumaphos. Serial analysis of gene expression (SAGE) was used to analyse differential gene expression in response to OP treatment and to compare the responses of OP-treated and -untreated r...

This paper proposes a procedure to compute abstractions of Discrete Event System (DES) models with the observer property (OP). The procedure, named OP-Search, is based on the OP-Verifier algorithm which verifies if a given natural projection has the observer property. In case OP fails for a projection in Σr of an automatonM , OP-Search modifiesM by relabelling transitions and incorporating the ...