We have considered infinite systems of nonlinear ODEs on the one-dimensional integer lattice which describes the activity in an excitatorily coupled network of excitable cells. For an ideal nonlinearity, we calculated the speed of propagation of an activity and derived the condition for its existence. We also studied the existence and stability of the traveling wave solution and gave, in the si...

10.2217/14750708.2.2.191 © 2 part of Modafinil is an oral wake-promoting agent, initially approved in December 1998 for the treatment of excessive sleepiness associated with narcolepsy. Based on the results of additional randomized, placebo-controlled studies, the indication for modafinil was expanded in January 2004 to include excessive sleepiness associated with obstructive sleep apnea/hypopn...

Congress and the states are moving rapidly to enact new legislation in the wake of a series of high-profile data security breaches by both private and public institutions. Bills have been introduced that would impose a variety of obligations on both businesses and public-sector entities in the event of a security breach, and provide remedies for individuals whose personal information was acquir...

This study discusses hydrodynamic effects of horizontal spoilers fixed on submarine pipelines. Numerical calculations are conducted to investigate the influences of the spoiler on flow profile, vortex shedding frequency, drag coefficients and lift coefficients. The calculation results demonstrate that attached horizontal spoilers could change the wake flow and enhance the self-burial of the pip...

the aerodynamics of road vehicles has frequently been studied in simplified geometries to separate the effect of various components on aerodynamic drag and on near wake flow dynamics. in this work, the characteristics of the near wake of a notch-back car model were investigated, using hot-wire anemometer. the main objectives of this study are to gain a better understanding of the flow structure...

Sleep-wake schedule disorder is defined by DSM-III-R as a mismatch between the normal sleep-wake schedule for a person's environment and his or her circadian sleep-wake pattern. The authors report a case in which a sleep-wake schedule disorder arose after a closed head injury. Sleep-wake schedule disorder has not been described as an outcome of closed head injury. As patients with sleep-wake sc...

How the circadian clock regulates the timing of sleep is poorly understood. Here, we identify a Drosophila mutant, wide awake (wake), that exhibits a marked delay in sleep onset at dusk. Loss of WAKE in a set of arousal-promoting clock neurons, the large ventrolateral neurons (l-LNvs), impairs sleep onset. WAKE levels cycle, peaking near dusk, and the expression of WAKE in l-LNvs is Clock depen...

Characteristics of enstrophy generation and entrainment velocity at the turbulent non-turbulent interface of a temporally evolving wake are studied using Direct Numerical Simulations (DNS), starting from the time instance when the instabilities develop to a fully turbulent state. Results reveal the dominant role of viscous effects compared to the production of enstrophy at the interface at all ...

We present experimental data to demonstrate that the far wake of a vertical-axis wind turbine (VAWT) exhibits features that are quantitatively similar to that of a circular cylinder with the same aspect ratio. For a fixed Reynolds number (Re ≈ 0.8 × 105) and variable tip-speed ratio, two-dimensional particle image velocimetry (PIV) is used to measure the velocity field in the wake of four diffe...

Potential adaptive wake vortex spacing systems may need to rely on wake vortex decay rather than wake vortex transport in reducing wake separations. Awake vortex takeoff-spacing system in particular will need to rely on wake decay. Ambient turbulence is the primary influence on wake decay away from the ground. This study evaluated 18 months of ambient turbulence measurements at Dallas/F't. Wort...