introduction: several lines of evidence suggest that the factor xiii (fxiii) 100 g/t polymorphism may influence susceptibility to deep venous thromboembolism (dvt). to explore this hypothesis, we investigated whether this polymorphism is associated with the predisposition to dvt. we also predict the possible impact of residue substitution at codons 34 (val34leu) in a subunits of the fxiii coagu...

Gastrointestinal (GI) bleeding commonly complicates anticoagulant therapy. We aimed to systematically review the published literature to determine the risk of thromboembolism, recurrent GI bleeding and mortality for patients on long-term anticoagulation who experience GI bleeding based on whether anticoagulation therapy was resumed. We performed a systematic review of phase III randomised contr...

In a prospective, randomized, parallel study, two regimens of platelet-suppressant therapy (PST)--dipyridamole-aspirin and pentoxifylline-aspirin--were compared with standard oral anticoagulation with warfarin in the prevention of prosthetic heart valve thromboembolism. In the entire group of 254 patients followed for 395.6 patient-years, the thromboembolic rate was significantly less in the wa...

BACKGROUND AND OBJECTIVES Evidence-based international guidelines recommend that all patients undergoing elective hip or knee arthroplasty receive thromboprophylaxis with low-molecular-weight heparin or adjusted-dose warfarin. Our objective was to determine what proportion of patients undergoing elective hip or knee arthroplasty actually receive recommended thromboprophylaxis according to inter...

results the incidence of diagnosed thrombo-embolic complication was 32 of 1,153 admitted patients (2.8%; 95% confidence interval: 1.9 to 3.9) with a median interval of 14 days after anti-tb treatment initiation. the incidence of dvt and pte was 2% and 1%, respectively. thrombo-embolic events and dvt were more common in men than in women: 4.2% versus 1.3% (p = 0.003) and 3.5% versus 0.4%, respec...

We present a case of idiopathic membranous glomerulonephritis that presented with venous thromboembolism and was successfully managed corticosteroid, cyclosporin, appropriate anticoagulant therapy. A 59-year old male patient referred to our nephrology department who had an outpatient history swelling in the feet flank pain detected proteinuria thrombosis inferior vena cava. Warfarin sodium trea...