نتایج جستجو برای: weighted gene co expression network analysis

تعداد نتایج: 4838665  

As an aromatic and colorful plant of substantive taste, saffron (Crocus sativus L.) owes such properties of matter to growing class of the secondary metabolites derived from the carotenoids, apocarotenoids. Regarding the critical role of microRNAs in secondary metabolic synthesis and the limited number of identified miRNAs in C. sativus, on the other hand, one may see the point how the characte...

2017
Yan Chen Yining Liu Min Du Wengang Zhang Ling Xu Xue Gao Lupei Zhang Huijiang Gao Lingyang Xu Junya Li Min Zhao

Integrating genomic information into cattle breeding is an important approach to exploring genotype-phenotype relationships for complex traits related to diary and meat production. To assist with genomic-based selection, a reference map of interactome is needed to fully understand and identify the functional relevant genes. To this end, we constructed a co-expression analysis of 92 tissues and ...

Journal: :Human molecular genetics 2014
Simone De Jong Marjolein Neeleman Jurjen J Luykx Maarten J ten Berg Eric Strengman Hanneke H Den Breeijen Leon C Stijvers Jacobine E Buizer-Voskamp Steven C Bakker René S Kahn Steve Horvath Wouter W Van Solinge Roel A Ophoff

Seasonal patterns in behavior and biological parameters are widespread. Here, we examined seasonal changes in whole blood gene expression profiles of 233 healthy subjects. Using weighted gene co-expression network analysis, we identified three co-expression modules showing circannual patterns. Enrichment analysis suggested that this signal stems primarily from red blood cells and blood platelet...

2017
Xiwen Liao Ketuan Huang Rui Huang Xiaoguang Liu Chuangye Han Long Yu Tingdong Yu Chengkun Yang Xiangkun Wang Tao Peng

BACKGROUND Molecular analysis is a promising source of clinically useful prognostic biomarkers. The aim of this investigation was to identify prognostic biomarkers for patients with early-stage pancreatic ductal adenocarcinoma (PDAC) after pancreaticoduodenectomy. METHODS An RNA sequencing dataset of PDAC was obtained from The Cancer Genome Atlas. Survival analysis and weighted gene co-expres...

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