PURPOSE We compared the efficacy of intravitreal ranibizumab and bevacizumab for treating neovascular age-related macular degeneration using an on-demand regimen. METHODS A total of 186 wet age-related macular degeneration eyes of 186 treatment-naïve patients were compared retrospectively (67 eyes treated with ranibizumab with 91 treated with bevacizumab). At baseline, mean age, best correcte...

age-related macular degeneration (amd) is the leading cause of blindness in old subjects. it is a multifactorial disease with both environmental and genetic factors playing some role in its pathogenesis. similar to many other genetic diseases, the inheritance pattern of amd does not fit into simple mendelian rules. these diseases are caused by the presence of multiple genetic factors and are ca...

purpose: to determine the correlation between body mass index (bmi) and exudative age-related macular degeneration (armd). methods: this case-control study was conducted on 60 patients with exudative armd and 60 controls, both aged over 50. age, sex, cigarette smoking and blood pressure were evaluated beside bmi. data analysis was performed by spss software, version 9.0 using pearson chi square...

Background Degenerative retinal diseases, including age related macular degeneration, glaucoma, and hereditary retinal dystrophies are major causes of blindness. The principal defect in these diseases is cell loss which is amenable to both cell based neuroprotective and neuroregenerative therapies. To briefly review the lines of research and potential candidates for cell based therapies among ...

Dear Editor, Neovascular (“wet”) age-related macular degeneration (AMD), diabetic macular edema (DME) and retinal vein occlusion (RVO) are amongst the most common causes of blindness.1-3 Traditionally, these conditions were treated with thermal laser photocoagulation, however, the advent of anti-vascular endothelial growth factor (VEGF) has revolutionised the treatment of these diseases.1,4,5 T...

BACKGROUND Angiogenesis is a contributing factor in some retinal diseases, hence the role of vascular endothelial growth factor (VEGF) as a common pathway in proliferative retinopathies. Bevacizumab has been found to be effective in the treatment of these diseases. The aim of this study was to review all cases of intravitreal bevacizumab given in the retinal unit of the University College Hospi...

Abnormal blood vessel growth in the retina is a hallmark of many retinal diseases, such as retinopathy of prematurity (ROP), proliferative diabetic retinopathy, and the wet form of age-related macular degeneration. In particular, ROP has been an important health concern for physicians since the advent of routine supplemental oxygen therapy for premature neonates more than 70 years ago. Since th...