and single-strand-specific cleavage. The two open complexes produce identical deoxyribonuclease I footprints and similar methylation interference/protection (one base shows different behaviour), indicating that both complexes are at the same binding site. The two open complexes, however, differ in the amount of unwinding in the 13 to + 3 region, as assayed by probes for singlestranded DNA. A fu...

Weighted A* (WA*) is a popular search technique that scales up A* while sacrificing solution quality. Recently, researchers have proposed two variants of WA*: KWA* adds diversity to WA*, and MSC-WA* adds commitment to WA*. In this paper, we demonstrate that there is benefit in combining them. The resulting MSC-KWA* scales up to larger domains than WA*, KWA* and MSC-WA*, which is rather surprisi...

In a longterm study, we have divided coeliac disease into two distinct entities (abortive and permanent) based on the occurrence of large granular lymphocytes and natural killer cells within the epithelium of the gut. The natural killer and large granular lymphocytes cells were characterised by either immunohistochemical or phase contrast microscopical procedures on the initial biopsies from 15...

According to Hofstadt, two phases can be distinguished in this disease: acute, and late. The first proceed one of 5 forms: purely encephalitic, Landry paralysis (always fatal), meningitic, myelitic and, finally, abortive.

Group II intron homing in yeast mitochondria is initiated at active target sites by activities of intron-encoded ribonucleoprotein (RNP) particles, but is completed by competing recombination and repair mechanisms. Intron aI1 transposes in haploid cells at low frequency to target sites in mtDNA that resemble the exon 1-exon 2 (E1/E2) homing site. This study investigates a system in which aI1 ca...

Glial erbB-1 and erbB-4 receptors are key components of the process by which neuroendocrine glial cells control LHRH secretion and the onset of female puberty. We now provide evidence that these two signaling systems work in a coordinated fashion to control reproductive function. To generate animals carrying functionally impaired erbB-1 and erbB-4 receptors, we crossed Waved 2 (Wa-2+/+) mice ha...

We investigate the effect of parasitoid phenology on host-parasitoid population cycles. Recent experimental research has shown that parasitized hosts can continue to interact with their unparasitized counterparts through competition. Parasitoid phenology, in particular the timing of emergence from the host, determines the duration of this competition. We construct a discrete-time host-parasitoi...