519 Biologically relevant information in acoustic signals often is present in its temporal structure. For example, the temporal relationships of particular acoustic elements are important for identifying human speech signals1, the proximity of a target in bat sonar2, songs in birds3, and calls in anuran amphibians4 (frogs and toads) and crickets5. In the sensory periphery, these signals are rep...

To cite: Rufino R, Marques BL, Costa CH. Thorax Published Online First: 19 December 2012 doi:10.1136/thoraxjnl-2012202827 A 32-year-old man worked as a subsistence farmer raising pigs and tending his small garden; he also kept cats and dogs. He reported fever, night sweats, weight loss of 10 kg over 3 months, haemoptysis and skin ulcers (figure 1). Radiography and chest CT scan (figure 2) showe...

not understand how she came to have parents so entirely different from herself. Spurred by various emotional urges she sets out on a crusade to '' live her own life.'' Usually she discovers herself inadequate to meet life as independently as she would like. She finds also that the consequences of independence are somewhat staggering. It is difficult to understand how anyone who has worked with ...

MOTIVATION We present a new probabilistic model of the evolution of RNA-, DNA-, or protein-like sequences and a software tool, Rose, that implements this model. Guided by an evolutionary tree, a family of related sequences is created from a common ancestor sequence by insertion, deletion and substitution of characters. During this artificial evolutionary process, the 'true' history is logged an...

The stopped-flow mixing technique was used to develop a very fast, sensitive and accurate method for determining total proteins. The method is based on the lower fluorescence of Rose Bengal caused by binding of the dye to the proteins. The decrease in the fluorescence intensity, measured at 572 nm with excitation 555 nm, was linearly related to protein concentration from 1.3 to 24.5 micrograms ...

This paper introduces a family of tetravalent graphs called rose window graphs, denoted by Rn(a, r), and investigates their symmetry properties. Four families of these graphs are shown to be edge-transitive and it is conjectured that every Rn(a, r) which is edge-transitive belongs to one of these families. Proofs and conjectures about the size of a dart-stabilizer and about regular maps contain...

It shows him in his Public Health Service uniform sometime after 1915, when he attained the rank of Assistant Surgeon General. Carter was a quarantine officer and a field epidemiologist, best known for his discovery in 1898 of the extrinsic incubation period of yellow fever. His discovery led directly to the historic finding by Reed, Carroll, Agra-monte, and Lazear in 1900 that mosquitoes are t...

Lake-level variations at Marcella Lake, a small, hydrologically closed lake in the southwestern Yukon Territory, document changes in effective moisture since the early Holocene. Former water levels, driven by regional palaeohydrology, were reconstructed by multiproxy analyses of sediment cores from four sites spanning shallow to deep water. Marcella Lake today is thermally stratified, being pro...