produced by mutants of Streptomyces peucetius^ , the daunorubicin2) producing microorganism, led to the discovery of doxorubicin (adriamycin)3) and other new anthracyclines4~8). By further mutagenic treatment of Streptomyces peucetius var. aureus, sl mutant of Streptomyces peucetius producing 4Odemethyl1 1 deoxydoxorubicin and analogues7), we have recently isolated other new mutant strains. Amo...

Cattle 's grazing of the locoweed Wahweap milkvetch (Astragalus lentiginosus var. wabweapensis) was evaluated on desert and foothill winter range during the winter of 1986 to 1987. Dry, dead stalks of Wahweap milkvetch that had grown in 1985 and 1986 made up 15% of cattle diets overall, and 24% of diets when cattle grazed gravelly benches where it was abundant. Nutrit ional quality of Wahweap m...

The concept of a medical savings account – in its purest form, a vehicle to allow people to save money to spend on health care – was initially developed in the United States in the 1970s. In the 1980s and 1990s the concept was translated into policy in a handful of countries, either as part of a private health insurance market (South Africa and the US) or to complement publicly-financed health ...

We analyze the properties of an interior point cutting plane algorithm that is based on a semi-infinite linear formulation of the dual semidefinite program. The cutting plane algorithm approximately solves a linear relaxation of the dual semidefinite program in every iteration and relies on a separation oracle that returns linear cutting planes. We show that the complexity of a variant of the i...

32P-HPLC is a recently published method to generate DNA adduct profiles after exposure to a complex of genotoxic substances. The low detection limit enables characterization of individual DNA adducts in the general population. The 32P-HPLC method was applied to human lymphocytes and granulocytes from Silesia, a polluted industrial region in the south of Poland. Human samples were collected at t...

This study investigates morphological differences between flakes produced via "core and flake" technologies and those resulting from bifacial shaping strategies. We investigate systematic variation between two technological groups of flakes using experimentally produced assemblages, and then apply the experimental model to the Cutting 10 Mid -Pleistocene archaeological collection from Elandsfon...

this experiment was conducted to assess the effects of daytime cutting management (p.m. vs. a.m. cut), ensiling duration and adding microbial inoculants on chemical composition of alfalfa silage. for this, second growth alfalfa harvested at the early bud stage of development after a sunny day at sundown (about 1900 h; pm alfalfa), whereas the second half was cut next day at sunup (about 0800 h;...

This article presents a process improvement study applied at a local paper manufacturing company based on customized Lean Six Sigma methodologies. More specifically, the DMAIC (Define, Measure, Analyze, Improve, and Control) project management methodology and various lean tools are utilized to streamline processes and enhance productivity. Two performance measures namely production rate and Ove...