This paper describes the fabrication of a microfluidic device for rapid immobilization of large numbers of live C. elegans for performing morphological analysis, microsurgery, and fluorescence imaging in a high-throughput manner. The device consists of two principal elements: (i) an array of 128 wedge-shaped microchannels, or clamps, which physically immobilize worms, and (ii) a branching netwo...

A growing awareness of the need to take into account social and contextual factors requirements engineering (RE) has led to expanded use of naturalistic inquiry (NI) methods, such as ethnography, for capturing relevant data. There is little debate about the potential value of NI to the development of systems; however, most previous discussions have emphasized practical techniques and benefits. ...

"To know that we know what we know, and that we do not know what we do not know, that is true knowledge." (Thoreau) There still is a lot we don't know yet about the environmental, health and safety impact of nanomaterials, but at least scientists are making progress in identifying the gaps – the 'known unknowns' as they call it. A group of researchers at the Technical University of Denmark (DTU...

Some people have argued that software is artistic. If so, what about malware? Only occasional, small-scale attempts have been made to create art using malware. We present “art worms,” worms which allow an artist to use the entire Internet as a canvas. These worms could be interactive, allowing an artist to stage a global performance, or non-interactive and automatic. Examples are given of artwo...

the aim of the present study was to assess the immunogenicity of under 30kda molecular weight proteins of hydatid cyst fluid and protoscoleces in dogs experimentaly infected with echinococcus granulosus. isolation of under 30 kda proteins performed using millipore filter. six dogs were used in three groups: 2 dogs with under 30 kda proteins of hydatid cyst fluid (group i); 2 dogs with proteins ...

Here in this study, we isolated 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG) from Curcuma longa L. and elucidated the lifespanextending effect of PGG using Caenorhabditis elegans model system. In the present study, PGG demonstrated potent lifespan extension of worms under normal culture condition. Then, we determined the protective effects of PGG on the stress conditions such as thermal and oxid...

The studies reported here were designed to investigate the role of the mutation eat-4 in the response to tap and in habituation in the nematode Caenorhabditis elegans. In C. elegans eat-4 has been found to affect a number of glutamatergic pathways. It has been hypothesized to positively regulate glutaminase activity and therefore glutamatergic neurotransmission. In the eat-4(ky5) loss-of-functi...

This paper serves worm defenders’ objective to improve their immunity to future active worms by giving them a deep insight into propagation characteristics of active worms from a worm authors’ perspective. Active worms self-propagate across networks by employing scanning, pre-generated target list, or internally generated target lists as their target discovery technique. We find target acquisit...

To clarify the existence of reinfection in children bearing an established Ascaris lumbricoides infection, the authors evaluated the weight and the length of worms collected from ten cases of ascaridiasis. The worm burden was greater than 27 worms in nine cases. In seven cases the weight and the length of worms showed little variation, with unimodal distribution of values, suggesting that all t...

Inequality in body sizes is a common feature in populations of helminth parasites, with potential consequences for egg production and population genetics. Inequalities in body lengths and the effects of intraspecific competition on worm length were studied in a species of mermithid nematode parasitic in the crustacean Talorchestia quoyana (Amphipoda: Talitridae). The majority of the 753 worms r...