BACKGROUND AND PURPOSE We determined which hemodynamic parameter independently characterizes the rupture status of middle cerebral artery (MCA) aneurysms using computational fluid dynamics analysis. METHODS In 106 patient-specific geometries of MCA aneurysms (43 ruptured, 63 unruptured), morphological and hemodynamic parameters were compared between the ruptured and unruptured groups. Multiva...

Environments in which Web service compositions (WSC) operate are often dynamic. We address the problem of which service to query for up-to-date information in order to adapt a hierarchical WSC, given that queries are not free. Previously, the value of changed information (VOC) has been proposed to select those services for querying whose revised non-functional information is expected to bring a...

For the rupture risk assessment of cerebral aneurysms, the blood flow is approximated using computational fluid dynamics (CFD). Unsteady CFD inflow conditions yield time-dependent vector fields, from which the wall shear stress (WSS), an important indicator for rupture risk in clinical research, is extracted. For WSS evaluation, its magnitude is usually color-coded on the aneurysm surface mesh....

PURPOSE To explore an alternative etiology for Purtscher retinopathy by literature review and fluid dynamic computational simulations of wall shear stress (WSS) profiles. METHODS Computer simulations were developed, incorporating posterior pole retinal microvascular flow parameters, to demonstrate WSS profiles at 90° and 45° angle artery/arteriolar branching. RESULTS Computer simulations re...

Due to the increase of published Web Services (WSs), finding the suitable WS that satisfies the user goals among discovered WSs still needs deep investigations. Certainly, QoS requirements represent a more appropriate and decisive factor to distinguish similar WSs. A lot of research efforts in this direction have been made but are still limited due to the complexity and diversity of QoS constra...

In order to study the role of blood-tissue interaction in the developing chicken embryo heart, detailed information about the haemodynamic forces is needed. In this study, we present the first in vivo measurements of the three-dimensional distribution of wall shear stress (WSS) in the outflow tract (OFT) of an embryonic chicken heart. The data are obtained in a two-step process: first, the thre...

Atherosclerosis is a disease caused due to formation of plaque into the artery. Increase in plaque affects the wall shear stress. The present study is performed to calculate wall shear stress in different geometries of stenosed carotid artery. A 2D model of different geometries is generated using CFD for NonNewtonian model. After this WSS of different geometries of stenosed arteries is calculat...

In multirate digital signal processing, we often encounter decimators, interpolators, and complicated interconnections of these with LTI filters. We also encounter cyclo-wide-sense stationary (CWSS) processes and linear periodically time-varying (LPTV) systems. It is often necessary to understand the effects of multirate systems on the statistical properties of their input signals. Some of thes...

Arteriovenous fistula (AVF) nonmaturation is currently a significant clinical problem; however, the mechanisms responsible for this have remained unanswered. Previous work by our group and others has suggested that anatomical configuration and the corresponding hemodynamic endpoints could have an important role in AVF remodeling. Thus, our goal was to assess the longitudinal (temporal) effect o...

Patient specific geometrical data on human coronary arteries can be reliably obtained multislice computer tomography (MSCT) imaging. MSCT cannot provide hemodynamic variables, and the outflow through the side branches must be estimated. The impact of two different models to determine flow through the side branches on the wall shear stress (WSS) distribution in patient specific geometries is eva...