Xeroderma pigmentosa (XP) is a condition inherited as an autosomal recessive trait and is characterized by photosensitivity, pigmentary changes, premature skin ageing and malignant tumour development resulting from the defect in DNA repair. The management of complications of XP, especially orofacial tumours entails an enormous surgical challenge to the clinicians. We present five cases of XP.

Epstein-Barr virus (EBV)-induced transformation effi ciencies were quantitated for peripheral blood leukocytes from two patients with xeroderma pigmentosum (XP) and a patient with the related disorder Cockayne's syndrome. By transformed centers or limiting dilution assays, there were no observed differences in transformation efficien cies between XP, Cockayne's syndrome, or normal adult leukocy...

TO THE EDITOR Individuals with xeroderma pigmentosum syndrome (XP) present an extremely high sensitivity to sunlight, with increased incidence of skin cancer (especially in sun-exposed areas), when compared to the normal population. Some XP patients can also display developmental complications and early aging features. A genetic defect in the nucleotide excision repair pathway (NER) was describ...

Epstein-Barr virus (EBV)-induced transformation effi ciencies were quantitated for peripheral blood leukocytes from two patients with xeroderma pigmentosum (XP) and a patient with the related disorder Cockayne's syndrome. By transformed centers or limiting dilution assays, there were no observed differences in transformation efficien cies between XP, Cockayne's syndrome, or normal adult leukocy...

XP is a code-oriented, light-weight software engineering methodology, suited merely for small-sized teams who develop software that relies on vague or rapidly changing requirements. Being very code-oriented, the discipline of systems engineering knows it as approach of incremental system change. In this contribution, we discuss the enhanced version of a concept on how to extend XP on large scal...

1 The author's work was supported by the Deutsche Forschungsgemeinschaft (DFG) as part of the PhD program “Enabling Technologies for Electronic Commerce” at Darmstadt University of Technology. Abstract The extreme Programming methodology (XP) relies on co-located collaboration of programming teams. This paper discusses problems and possible solutions when distributed teams decide to do XP. Comm...

XP is a code-oriented, light-weight software engineering methodology, suited merely for small-sized teams who develop software that relies on vague or rapidly changing requirements. Being very code-oriented, the discipline of systems engineering knows it as approach of incremental system change. In this contribution, we discuss the enhanced version of a concept on how to extend XP on large scal...

PURPOSE Xanthogranulomatous prostatitis (XP) is a rare form of nonspecific granulomatous prostatitis that can clinically mimic high-grade prostatic carcinoma. It is difficult to diagnose it definitely in clinical settings. METHODS We report a case of XP with prostate-rectal fistula and review the relevant literatures. RESULT A 75-year-old man presented with rectal bleeding when he urinated....

Outsourcing is common for software development, and is the context for many projects using agile development processes. This paper presents two case studies concentrating on the customer role in projects using outsourcing and extreme programming (XP). The studies follow an interpretive approach based on in-depth interviews, and suggest some tensions between some contractual arrangements in outs...

Xeroderma pigmentosum (XP) is a genetic disease in which DNA repair mechanisms are impaired. Cisplatin (CDDP) exerts cytotoxic effects by forming mainly intrastrand DNA cross-links, and sensitivity to CDDP depends on the DNA repair system. Several in vitro studies have suggested that treatment with CDDP may cause enhanced adverse events as well as anti-tumor activity in cancer patients with XP....