OBJECTIVE A case control study to identify risk factors for burning mouth syndrome (BMS). MATERIAL AND METHODS Quantitative analysis was carried out on the total salivary flow at rest and stimulated; subjective xerostomia, ingestion of medicines and the psychological states of anxiety and depression in 40 patients with BMS and 40 controls. RESULTS The ANOVA analysis showed significant diffe...

PURPOSE The aim of this study was to develop a multivariate logistic regression model with least absolute shrinkage and selection operator (LASSO) to make valid predictions about the incidence of moderate-to-severe patient-rated xerostomia among head and neck cancer (HNC) patients treated with IMRT. METHODS AND MATERIALS Quality of life questionnaire datasets from 206 patients with HNC were a...

Introduction: Radioisotope scanning is the best method for objective assessment of salivary gland function. Thus, it was used in a randomized trial of concomitant pilocarpine for assessment of radiation-induced xerostomia, in addition to subjective evaluation by an approved questionnaire and objective standard xerostomia grading. Methods: Patients randomized in placebo-controlled trial of...

Objectives: The aim of the study was to determine the frequency and nature of oral manifestations secondary to use of cardiovascular drugs. Methods: Six hundred and three patients attending the general medicine departments of Bapuji hospital and Chigeteri Government hospital, Davangere, were evaluated for oral signs and symptoms like oral dryness, alteration in the taste or burning sensation an...

OBJECTIVE To determine the long-term effects of acupuncture in patients with xerostomia of different etiologies and the influence of additional treatment. DESIGN Retrospective study. SUBJECTS Seventy patients, between the ages of 33 and 82, with xerostomia due to primary and secondary Sjögren's syndrome, irradiation and other causes were included. The median duration of xerostomia was 32 mo...

OBJECTIVES To assess salivary flow in older patients with type 2 diabetes mellitus (DM2) and its association with xerostomia. METHODS Cross-sectional clinical study conducted with older patients diagnosed with type 2 diabetes for at least one year receiving treatment at the Integrated Center for Diabetes and Hypertension of Ceará (CIHD) in the city of Fortaleza, Ceará, Northeastern Brazil. Or...

Purpose: Xerostomia, sialoadenitis, taste dysfunction and nausea are well known toxicities following high dose radioactive iodine (RAI) treatment for well-differentiated thyroid cancer. This prospective study sought to determine the incidence rates for RAI adverse effects and to determine, whether the radioprotector, amifostine could decrease the duration of the adverse effects in single treatm...

Xerostomia or dry mouth is one of the most common and disturbing adverse effects following radiotherapy for head and neck cancer (HNC). This complication strongly increases the risk for dental caries, difficulties with chewing, swallowing and sleep disorders with significant impact on patients’ quality of life. Current treatment approaches of xerostomia are often difficult and bring in many cas...