Increased recent interest in the middle latency response (MLR) has necessitated a clarification of the possible effects of anesthesia on the response. Our study was designed to examine the changes, in the guinea pig MLR, which occurred during anesthesia with ketamine, xylazine or both ketamine and xylazine. Under anesthesia the response remained present and the threshold remained stable. After ...

Objective- This study was performed to investigate the analgesic effects of lidocaine, xylazine and lidocaine/xylazine combination in epidural anesthesia in dromedary camels. Design- Experimental Study Animals- Fifteen healthy immature dromedary camels Methods- The camels were randomly designed in 3 equal groups. In group L: lidocaine 2% (0.22 mg/kg), in group X: xylazine 2% (0.17 mg/kg), an...

Objective- This  study  was  performed  to  investigate  the  analgesic  effects  of  lidocaine, xylazine and lidocaine/xylazine combination in eye regional anesthesia. Design- Experimental Study. Animals- Twenty adult goats were randomly designed in 4 groups. Procedures- In group L: 10 ml mixture of lidocaine 2% (5 mg/kg bw) and normal saline, In group LX: 10 ml mixture of lidocaine 2% (5 mg/k...

Objective- To compare the time of onset, duration of action and the extent of analgesia produced by a lidocaine/xylazine combination with that produced by lidocaine and xylazine alone after injection into the caudal extradural space of the Iranian river buffalo. Design- Observer-blind prospective descriptive trial, Latin square design.   Animals-  Eleven adult (aged over 2 years) female non-...

Objective: It was aimed to investigate the effects of ketamine combination administered with xylazine used for general anesthesia in dogs on arterial blood pressure, heart rate, and body temperature.Materials Methods: In study, a total 20 dogs, 14 females 6 males, from various breeds ages 1 5, which undergone elective ovariohysterectomy or castration according weights. mg/kg (xylazine hydrochlo...

Sixteen captive female red deer were successfully anesthetized to surgically implant a telemetry system. The deer were immobilized with (mean±SD) 1.79±0.29 mg/kg xylazine and 1.79±0.29 mg/kg tiletamine/zolazepam given intramuscularly with a dart gun. Anesthesia was maintained for 69±2 min using a total intravenous protocol with a catheter placed in the jugular vein. Group X received xylazine (0...

Currently, experimental animals are widely used in biological and medical research. However, the scientific community has raised several bioethical concerns, such as number of required to achieve reproducible statistically relevant results. These concerns involve aspects related pain, discomfort, unwanted animal loss. Retrospectively, we compare two different approaches for anesthesia dosage: a...

The aim of the present study was to explore effect three selective sedative/tranquilizer drugs i.e. Xylazine(XZ), Acepromazine(AC), and Diazepam(DZ) on normal physiological parameters such aspulse, respiration, body temperature serum glucose.All Xylazine, Acepromazine, Diazepam were used at dose rate 8mg/kg, 5 mg/kgand diazepam1mg/kg respectivelythrough intramuscular route(I.M.)in six healthy r...