Background & Aims: Despite improvements in public health in Iran, cutaneous leishmaniasis has become a growing health issue. About 90% of cutaneous leishmaniasis cases occur in 8 countries including Iran. Kala-azar or visceral leishmaniasis, as an important parasitic disease, is endemic in some areas of Iran. Mapping the distribution of parasitic diseases and determining their relations to geog...

Leishmaniasis has long been known as a significant public health challenge in many parts of Iran. Phlebotomus papatasi and P. sergenti are the vectors of Zoonotic Cutaneous Leishmaniasis and Anthroponotic Cutaneous Leishmaniasis respectively, and 5 species of sand flies including P. kandelakii, P. neglectus, P. perfiliewi, P. keshishiani and P. alexandri are considered as probable vectors of Zo...

zoonotic cutaneous leishmaniasis (zcl) is an increasing and important public health problem in iran. the use of repellents is recommended as one of the important means of personal protection against vectors of zcl. this paper reports the repellency effect of the plant myrtle, myrtus communis (myrtaceae), essential oil for protection against 3-7-day-old unfed females of the sandfly, phlebotomus ...

following an epidemiological survey of zoonotic cutaneous leishmaniosis (zcl) in some villages of badrood, a rural district north of the city of natanz, central iran, phlebotomus (phlebotomus ) papatasi scopoli were found to be naturally infected with leishmania (leishmania) major zymodeme mon-26. sandflies were collected and dissected biweekly from rodent burrows during sandfly season, april- ...

BACKGROUND Leishmaniasis is a zoonotic disease caused by species of protozoa of the genus Leishmania. In recent years, incidence of cutaneous leishmaniasis has increasing trend in Golestan Province, North of Iran. The aim of the present study was to identify the frequency of cutaneous leishmaniasis using PCR-RFLP in patients referred to Kalaleh Health Center, during 2013-14. METHODS This desc...

There are many strategies to control leishmaniasis, but majority of them are inadequate. Killed Leishmania vaccine (KLV) has been applied for its immunogenicity in human and mouse model. Bacillus Calmette-Guerin (BCG) as adjuvant is an immune-modulator inducing humoral and cellular immune responses during zoonotic cutaneous leishmaniasis (ZCL). Both KLV and BCG have been applied for their immun...

BACKGROUND Great gerbils, Rhombomys opimus, are the main reservoir host of zoonootic cutaneous leishmaniasis (ZCL) in Iran and neighboring countries. Based on morphological traits two subspecies R. opimus sodalis and R. opimus sargadensis have reported in the country. However, variation in infection rate and signs to Leishmania parasites, phenotype, size, and sexual polymorphisms demand more de...

BACKGROUND Zoonotic cutaneous leishmaniasis (ZCL) is an increasing public health problem in some endemic regions. Horseradish peroxidase (HRP) conjugated rabbit anti-Rhombomys opimus (R. opimus) Ig is needed for immunoblotting and ELISA tests used to explore the immune response of the rodents against the sand fly saliva. In this study, the production of HRP conjugated rabbit anti-R. opimus Ig w...

in 5 villages in isfahan area, with a population of 1368, rodents were successfully controlled using poisened bait with zinc phospheid, with 300 meters of houses and built up area. in another 5 villages with a population of 1471, rodent burrows were dusted with ddt within the same distance, without any effect on sandflies. a third group of 5 villages was kept as control. the incidence of cutane...