نتایج جستجو برای: zwitterionic drugs
تعداد نتایج: 226648 فیلتر نتایج به سال:
Unexpected selective alkaline periodate oxidation of chitin for the isolation of chitin nanocrystals
No periodate oxidation on chitin? For the first time, direct selective alkaline of chitin led to isolation ordered domains as uniform anisotropic and zwitterionic ChNCs after simultaneous removal non-ordered domains.
Electromembrane extraction (EME) of the polar zwitterionic drugs, anthracyclines (ANT, doxorubicin, daunorubicin and its metabolite daunorubicinol), from rabbit plasma was investigated. The optimized EME compared to conventional sample pretreatment techniques such as protein precipitation (PP) liquid-liquid (LLE), mainly in terms reliability, recovery matrix effect. In addition, phospholipids p...
Zwitterionic polymer-based dual thermoresponsive micelles were synthesized. Structural investigations revealed that they exhibit both liquid–liquid phase separation and coil–globule transition the size scale of each is different.
Soft amphiphilic nanotubes are capped with vesicles comprised of either overall neutral, zwitterionic phospholipids, or those that carry a net charge. The phase transition temperature of the zwitterionic phospholipids plays a crucial role in the phase separation that leads to the end-capped nanotubes. The cationic vesicle caps can be loaded into the nanotubes via osmosis whereas the anionic ves...
This focused review addresses the fundamental development of nonfouling zwitterionic poly(sulfobetaine methacrylate) (polySBMA) coatings on a wide range of interfaces and membranes in our laboratory for use in the development of hemocompatible medical devices. The molecular designs of zwitterionic interfaces (for example, surface packing density, grafting coverage, polymer chain conformation an...
We report the results of a multidisciplinary research effort where the methods of computational photochemistry and retrosynthetic analysis/synthesis have contributed to the preparation of a novel N-alkylated indanylidene-pyrroline Schiff base featuring an exocyclic double bond and a permanent zwitterionic head. We show that, due to its large dipole moment and efficient photoisomerization, such ...
The ability of small particles to associate with DNA and to transport it to desired targets without being subjected to interferences can make them efficient vehicles for gene delivery. Keeping these requirements in mind, zwitterionic latex particles with two different functional tethers were chosen for studying their interaction with DNA as vehicle complexes. From adsorption and electrokinetic ...
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