We examined the effects of dietary restriction (DR) and age on ss-cell function and peripheral insulin sensitivity in rhesus monkeys. A semipurified diet was provided either ad libitum for approximately 8 hours/day to controls (C) or as approximately 70% of baseline intake to restricted (R) animals for 10 years. The minimal model of C-peptide secretion and kinetics and the labeled 2-compartment...

The dynamics of velocity fluctuations governed by the Burgers equation, driven by the white-in-time random forcing function with f fsx 1 r , td 2 fsx, t0dg2 ~ rdst 2 t0d is considered on the interval 0 , x , L. The properties of the probability density function of velocity differences PsDu, rd are investigated for the three cases j ­ h0; 1y2; 2j. It is shown that the tail of the probability den...

Based on the field emission (FE) results achieved with regular test arrays of gold [1] and platinum [2] nanowire (NW) patches, FE cathodes (Ø 5 mm) with a triangular patch array (Ø 150 μm, pitch 320 μm) of cylindrical AuNW (10 cm, Ø 200 nm, length 12 μm) were fabricated by means of a shadow mask during heavy ion irradiation of polycarbonate foils. The emitter distribution and local properties o...

Maintenance of nucleosomal structure in the cell nuclei is essential for cell viability, regulation of gene expression and normal aging. Our previous data identified a key intermediate (a small intranucleosomal DNA loop, Ø-loop) that is likely required for nucleosome survival during transcription by RNA polymerase II (Pol II) through chromatin, and suggested that strong nucleosomal pausing guar...

A series of 3 experiments were conducted to examine the behaviour of Japanese-speaking learners of French (JSL) concerning the perception and production of French /u/, /y/ and /ø/, compared with English-speaking learners of French, in order to examine how L2 (second language) vowels which do not have phonemic and/or phonetic equivalents in L1 (native language) are acquired by learners. The resu...

SH signals recorded by an array of four broadband (Benioff 1-90) instruments, run by Caltech, are inspected for evidence of a lower mantle shear wave velocity discontinuity previously detected using WWSSN data. Deep focus earthquakes beneath Argentina span the distance range 78 ø to 82 ø from the array, where the triplication in the travel time curve produced by the discontinuity is expected to...