Abstract Objectives This study reports a rare case of primary extragenital choriocarcinoma in the spleen presenting as acute abdominal pain. We expect this to provide more valuable information for clinicians future. Case presentation The patient was 22-year-old woman, with healthy child and history bilateral ovarian cyst resection week before, who presented severe sudden pain left upper abdomen...

Background: Tubal ectopic pregnancy is potentially life-threatening with an estimated incidence of 1% to 2% all pregnancies the wide availability transvaginal ultrasound and quantitative serum beta human chorionic gonadotropin (β-hCG) assay; can be diagnosed early, leading successful management without resort surgery. Objective: Evaluation β-hCG levels between days 4 7 as a predictor methotrexa...

Objective To compare the results of expectant management, single and multidose methotrexate (MTX) and surgical management of ectopic pregnancy (EP). Materials and Methods In this retrospective cohort study, the original files of 233 patients who were treated for EP between May 2009 and December 2016 were analyzed. The patients were assigned to the following groups based on the applied treatme...

Prenatal diagnosis of chromosomal aneuploidies is the most frequent prenatal test offered to pregnant women. In most cases, they are recommended in the following circumstances: maternal age of 35 years or above; positive firstor second-trimester screening test results, and increased risk of fetal aneuploidies due to family history. During the first trimester, screening tests include: nuchal tra...

Abstract Study question Is it possible to predict clinical pregnancy using Machine Learning models on day 6 after embryo transfer an acceptable degree of certainty? Summary answer Using selected biochemical markers is build a machine learning model pregnancy. What known already Human chorionic gonadotropin (β-hCG) considered the main early predictor Due fact that highest percentage spontaneous ...

OBJECTIVE To report an extremely rare case of spontaneous uterine perforation of choriocarcinoma with negative beta-human chorionic gonadotropin (β-hCG) post-chemotherapy. CLINICAL PRESENTATION AND INTERVENTION We present a 35-year-old choriocarcinoma patient whose serial serum β-hCG levels following a fifth course of chemotherapy had been within the normal range, but who developed spontaneou...

Nowadays, the prevalence of Multiple Myeloma (MM) seems to have been increasing among young females. Here, we report that thalidomide is contraindicated in pregnant women diagnosed with MM and those desirous of subsequent pregnancy. In this case report, we compared the clinical response of Thalidomide-Dexamethasone therapy in a post-abortive woman with persistently elevated β-hCG levels due to ...

Background: Patients with ectopic pregnancy and low serum β-HCG concentrations are commonly treated systemic methotrexate. Aim: To compare the outcome of methotrexate versus expectant management for females presenting pregnancy. Study design: Randomized controlled trial. Methodology: Females (n=140) were enrolled in study. Blood sample was taken beta-HCG noted. Then randomly divided two groups ...

Objectives: To study the role of β – hCG in pathogenesis of preeclampsia and its association with severity of preeclampsia. Materials and Methods: The prospective randomized study was conducted on 500 pregnant women of gestational pregnancy between 12 24 weeks with singleton pregnancy. According to American college of obstetrics and gynecology [ACOG, 2013], patients were classified into three g...

Objective(s): Amyloid β plaques, in Alzheimer’s disease, are deposits in different areas of the brain such as prefrontal cortex, molecular layer of the cerebellum, and the hippocampal formation. Amyloid β aggregates lead to the release of cytochrome c and finally neuronal cell death in brain tissue. hCG has critical roles in brain development, neuron differentiation, and function. Therefore, we...