BACKGROUND This study advances the clinical development of the RTS,S/AS01B candidate malaria vaccine to malaria endemic populations. As a primary objective it compares the safety and reactogenicity of RTS,S/AS01B to the more extensively evaluated RTS,S/AS02A vaccine. METHODOLOGY A Phase IIb, single centre, double-blind, controlled trial of 6 months duration with a subsequent 6 month single-bl...

Safe regression test selection (RTS) techniques let software testers reduce the number of test cases that need to be rerun to revalidate new versions of software, while ensuring that no fault-revealing test case (in the existing test suite) is excluded. Most previous work on safe regression test selection has focused on speciic safe RTS algorithms, rather than addressing the theoretical foundat...

BACKGROUND Studies of non-health-care work environments indicate that non-managerial employee job satisfaction is higher in companies that use participative (as opposed to autocratic) decision making. It has not been determined whether managerial decision-making style influences job satisfaction among respiratory therapists (RTs) and which managerial decision-making style RTs prefer. METHODS ...

BACKGROUND Previous trials of the RTS, S malaria candidate vaccine have shown that this vaccine is safe, tolerated and immunogenic. The development plan for this vaccine aims at administering it in the first year of life through the Expanded Program on Immunization (EPI). The objective was to evaluate the safety and reactogenicity of RTS, S/AS02D (0.5 ml dose), a pediatric formulation of GlaxoS...

Less than 50% of athletes pass criteria to return to sports (RTS) 6 months after ACL reconstruction (ACLR). Using data on 38 noncopers, we hypothesized that preoperative age, quadriceps strength index (QI), and knee flexion moments (KFM) during gait would predict the ability to pass/fail RTS criteria and that preoperative quadriceps strength gains would be predictive of passing RTS criteria. Ga...

BACKGROUND Anterior cruciate ligament (ACL) rupture is a significant injury in National Basketball Association (NBA) players. HYPOTHESES NBA players undergoing ACL reconstruction (ACLR) have high rates of return to sport (RTS), with RTS the season following surgery, no difference in performance between pre- and postsurgery, and no difference in RTS rate or performance between cases (ACLR) and...

Rubinste in-Taybi syndrome (RTS) is a rare developmental disorder characterized by craniofacial dysmorphisms, broad thumbs and toes as well as mental and statural deficiencies. RTS has a prevalence of 1 in 330,000 births and usually occurs sporadically, although it can be inherited as an autosomal dominant disorder. The diagnosis is based on characteristic features. The main clinical symptoms a...